PACAP Related Peptide Polyclonal Antibody | anti-Adcyap1 antibody
Anti - PACAP Related Peptide (Pituitary Adenylate Cyclase Activating Polypeptide Related Peptide, PRP)
Gene Names
Adcyap1; PACAP
Applications
ELISA, Western Blot
Purity
Purified by immunoaffinity chromatography.
Synonyms
PACAP Related Peptide; Polyclonal Antibody; Anti - PACAP Related Peptide (Pituitary Adenylate Cyclase Activating Polypeptide Related Peptide; PRP); PACAP Related Peptide (Pituitary Adenylate Cyclase Activating Polypeptide Related Peptide; anti-Adcyap1 antibody
Host
Host: Rabbit
Source: Human
Source: Human
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes human PACAP Related Peptide.
Purity/Purification
Purified by immunoaffinity chromatography.
Form/Format
Affinity Purified
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
Concentration
~1mg/ml (varies by lot)
Applicable Applications for anti-Adcyap1 antibody
ELISA, Western Blot
Application Notes
Suitable for use in ELISA and Western Blot. Other applications not tested.
Dilution: ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. See P1775-01M.
Western Blot: 1-10ug/ml using ECL technique.
Optimal dilutions to be determined by the researcher.
Dilution: ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. See P1775-01M.
Western Blot: 1-10ug/ml using ECL technique.
Optimal dilutions to be determined by the researcher.
Immunogen
11aa peptide from human PRP. Location
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Adcyap1 antibody
Vasoactive intestinal peptide (VIP) is a 28-aminoacid peptide (human, chr 6q26-q27). Expressed and secreted by neurons innervating primary and secondary immune organs such as lymph nodes with a Mol.wt of 20kD. VIP is a potent neurotrophic factor causes vasodilation, lowers arterial blood pressure, and relaxes the smooth muscle of trachea, stomach and gall bladder. VIP also modulates several T-lymphocyte activities including motility, cytokine production, proliferation and apoptosis, VIP exerts its biological activity by binding to two closely related class II G-protein-coupled receptors VPAC-1 and VPAC-2 beside this VIP has its own receptors VIPR1&2 (Vasoactive Intestinal Polypeptide Receptor 1&2) and VIPRRP (VIP receptor-gene repressor protein). VIP shows similarities to glucagon, secretin and gastric inhibitory peptide (GIP) as such it has been considered a member of the glucagon-secretin family. The VIP is 100% conserved in mouse, rat and human. VIP is considered to be a viable candidate for the development of treatments for rheumatoid arthritis, since treatment with VIP significantly reduced incidence of severity of arthritis, the therapeutic effect of VIP was associated with downregulation of both inflammatory and autoimmune components of the disease. Pituitary adenylate cyclase-activating polypeptide (PACAP) is a bioactive peptide (human 176aa, 175 each in mouse and rat) that was originally isolated from ovine hypothalamus on the basis of its ability to stimulate adenylate cyclase and functions as a neurotransmitter and neuromodulator The N-terminal amino acid sequence of PACAP shows 68% identity with VIP and more limited similarity with growth hormone-releasing hormone.
Product Categories/Family for anti-Adcyap1 antibody
References
• 1. Bodner,M (1985) PNA,82, 3548-35512. Delgado, M (2001) Nature Med, 7, 563-5683. Hamelink, C et al(2002) PNA Sci,99, 461-4664. Hashimoto, H. et al(2001) PNA sci 98,13355-60;5. Gotoh, E.(1998) Biochem. Int, 17, 555-562
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,381 Da
NCBI Official Full Name
pituitary adenylate cyclase-activating polypeptide
NCBI Official Synonym Full Names
adenylate cyclase activating polypeptide 1
NCBI Official Symbol
Adcyap1
NCBI Official Synonym Symbols
PACAP
NCBI Protein Information
pituitary adenylate cyclase-activating polypeptide
UniProt Protein Name
Pituitary adenylate cyclase-activating polypeptide
Protein Family
UniProt Gene Name
Adcyap1
UniProt Synonym Gene Names
Pacap
UniProt Entry Name
PACA_MOUSE
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Product Notes
The Adcyap1 adcyap1 (Catalog #AAA612633) is an Antibody produced from Host: Rabbit Source: Human and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's PACAP Related Peptide can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot. Suitable for use in ELISA and Western Blot. Other applications not tested. Dilution: ELISA: 0.5-1ug/ml; Control peptide can be used to coat ELISA plates at 1ug/ml. See P1775-01M. Western Blot: 1-10ug/ml using ECL technique. Optimal dilutions to be determined by the researcher. Researchers should empirically determine the suitability of the Adcyap1 adcyap1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PACAP Related Peptide, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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