Rabbit P311 Polyclonal Antibody | anti-NREP antibody
P311 Antibody
Gene Names
NREP; P311; PTZ17; SEZ17; D4S114; C5orf13; PRO1873
Reactivity
Human, Mouse, Rat
Applications
ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
P311; Polyclonal Antibody; P311 Antibody; 3.1 gene; C5orf13; Chromosome 5 open reading frame 13; D4S114; Neuronal protein 3.1; Neuronal regeneration related protein; Neuronal regeneration related protein homolog (rat); Neuronal regeneration related protein homolog; NP311_HUMAN; NREP; PRO1873; Protein p311; PTZ17; SEZ17; anti-NREP antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Specificity
P311 Antibody detects endogenous levels of total P311.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid. Rabbit IgG in phosphate buffered saline, pH7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Applicable Applications for anti-NREP antibody
ELISA (EIA)(peptide)
Application Notes
ELISA(peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from Human MYOCD.
Conjugation
Unconjugated
Post Translational Modifications
Phosphorylated on Ser-59. Phosphorylation decreases stability and activity.
Subunit Structure
Interacts with the latency-associated peptides (LAP) of TGFB1 and TGFB2; the interaction results in a decrease in TGFB autoinduction (By similarity). Interacts with FLNA.
Tissue Specificity
Expressed in lung (at protein level).
Function
May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration (By similarity). May also have functions in cellular differentiation (By similarity). Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis (By similarity). Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3 (By similarity). May play a role in the regulation of alveolar generation.
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
7,909 Da
NCBI Official Full Name
neuronal regeneration-related protein isoform c
NCBI Official Synonym Full Names
neuronal regeneration related protein
NCBI Official Symbol
NREP
NCBI Official Synonym Symbols
P311; PTZ17; SEZ17; D4S114; C5orf13; PRO1873
NCBI Protein Information
neuronal regeneration-related protein; protein p311; neuronal protein 3.1; neuronal regeneration related protein homolog
UniProt Protein Name
Neuronal regeneration-related protein
Protein Family
UniProt Gene Name
NREP
UniProt Synonym Gene Names
C5orf13; P311
UniProt Entry Name
NREP_HUMAN
Uniprot Description
P311: May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration. May also have functions in cellular differentiation. Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q22.1
Cellular Component: cytoplasm; nucleus
Molecular Function: protein binding
Biological Process: regulation of transforming growth factor beta receptor signaling pathway; regulation of neuron differentiation; axon regeneration
Research Articles on NREP
1. Protein HYI may closely bind with protein P311 by an alpha helix in hypertrophic scar fibroblasts.
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Product Notes
The NREP nrep (Catalog #AAA9629647) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P311 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's P311 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the NREP nrep for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P311, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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