Western Blot (WB)
(Western blot analysis of extracts of K562 cell lysate, using P2RY4 antibody.)
Rabbit anti-Human P2RY4 Polyclonal Antibody | anti-P2RY4 antibody
P2RY4 (NRU, P2P, UNR, P2Y4, P2Y Purinoceptor 4) (PE)
WB: 1:500-1:2000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of extracts of K562 cell lysate, using P2RY4 antibody.)
Western Blot (WB)
(Western blot analysis of extracts of K562 cell lysate, using P2RY4 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using P2RY4 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using P2RY4 antibody.)
NCBI and Uniprot Product Information
NCBI Description
The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is responsive to uridine nucleotides, partially responsive to ATP, and not responsive to ADP. [provided by RefSeq, Jul 2008]
Uniprot Description
P2RY4: Receptor for UTP and UDP coupled to G-proteins that activate a phosphatidylinositol-calcium second messenger system. Not activated by ATP or ADP. Belongs to the G-protein coupled receptor 1 family.
Protein type: Membrane protein, integral; Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: Xq13
Cellular Component: basolateral plasma membrane; integral to plasma membrane; apical plasma membrane; plasma membrane
Molecular Function: purinergic nucleotide receptor activity, G-protein coupled; UTP-activated nucleotide receptor activity; ATP binding; uridine nucleotide receptor activity
Biological Process: elevation of cytosolic calcium ion concentration; transepithelial chloride transport; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating)
Research Articles on P2RY4
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Product Notes
The P2RY4 p2ry4 (Catalog #AAA6430268) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The P2RY4 (NRU, P2P, UNR, P2Y4, P2Y Purinoceptor 4) (PE) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's P2RY4 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), Western Blot (WB). IHC: 1:50-1:100 WB: 1:500-1:2000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the P2RY4 p2ry4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "P2RY4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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