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Western Blot (WB) (Western blot analysis of p23 expression in Jurkat (A), NIH3T3 (B) whole cell lysates.)

Rabbit p23 Polyclonal Antibody | anti-PTGES3 antibody

Anti-p23 Antibody

Gene Names
PTGES3; P23; TEBP; cPGES
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Monkey
Applications
Western Blot, Immunohistochemistry
Purity
The antibody was purified by immunogen affinity chromatography.
Synonyms
p23; Polyclonal Antibody; Anti-p23 Antibody; P23; TEBP; Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Telomerase-binding protein p23; anti-PTGES3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Bovine, Chicken, Monkey
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of p23 protein.
Purity/Purification
The antibody was purified by immunogen affinity chromatography.
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
139
Applicable Applications for anti-PTGES3 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB (1/500 - 1/1000), IHC (1/100 - 1/200)
Immunogen
KLH-conjugated synthetic peptide encompassing a sequence within the center region of human p23. The exact sequence is proprietary.
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of p23 expression in Jurkat (A), NIH3T3 (B) whole cell lysates.)

Western Blot (WB) (Western blot analysis of p23 expression in Jurkat (A), NIH3T3 (B) whole cell lysates.)

Immunohistochemistry (IHC)

(Immunohistochemical analysis of p23 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)

Immunohistochemistry (IHC) (Immunohistochemical analysis of p23 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.)
Related Product Information for anti-PTGES3 antibody
Rabbit polyclonal antibody to p23

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
16,476 Da
NCBI Official Full Name
prostaglandin E synthase 3 isoform b
NCBI Official Synonym Full Names
prostaglandin E synthase 3 (cytosolic)
NCBI Official Symbol
PTGES3
NCBI Official Synonym Symbols
P23; TEBP; cPGES
NCBI Protein Information
prostaglandin E synthase 3
UniProt Protein Name
Prostaglandin E synthase 3
Protein Family
UniProt Gene Name
PTGES3
UniProt Synonym Gene Names
P23; TEBP; cPGES
UniProt Entry Name
TEBP_HUMAN

Uniprot Description

TEBP: Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor- mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Belongs to the p23/wos2 family.

Protein type: Nuclear receptor co-regulator; Isomerase; EC 5.3.99.3; Transferase; Chaperone

Chromosomal Location of Human Ortholog: 12q13.3|12

Cellular Component: nucleoplasm; chromosome, telomeric region; cytoplasm; telomerase holoenzyme complex; cytosol; nucleus

Molecular Function: telomerase activity; protein binding; unfolded protein binding; prostaglandin-E synthase activity

Biological Process: RNA-dependent DNA replication; cyclooxygenase pathway; arachidonic acid metabolic process; prostaglandin biosynthetic process; signal transduction; telomere maintenance

Research Articles on PTGES3

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Product Notes

The PTGES3 ptges3 (Catalog #AAA8216565) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-p23 Antibody reacts with Human, Mouse, Rat, Bovine, Chicken, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's p23 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB (1/500 - 1/1000), IHC (1/100 - 1/200). Researchers should empirically determine the suitability of the PTGES3 ptges3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "p23, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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