Goat anti-Human, Mouse OTUD7A Polyclonal Antibody | anti-OTUD7A antibody

OTUD7A (OTU Domain-containing Protein 7A, Zinc Finger Protein Cezanne 2, C15orf16, CEZANNE2, OTUD7)

Cat. Num. AAA646773

• Gene Names: OTUD7A; OTUD7; C15orf16; C16ORF15; CEZANNE2
• Reactivity: Human, Mouse
• Applications: ELISA
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: OTUD7A; Polyclonal Antibody; OTUD7A (OTU Domain-containing Protein 7A; Zinc Finger Protein Cezanne 2; C15orf16; CEZANNE2; OTUD7); Anti -OTUD7A (OTU Domain-containing Protein 7A; anti-OTUD7A antibody

• Host: Goat
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Specificity: Recognizes OTUD7A. Species sequence homology: Human and mouse.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

• Applicable Applications for anti-OTUD7A antibody: ELISA (EL/EIA)
• Application Notes: Suitable for use in ELISA.; Dilution: ELISA: 1:1000
• Immunogen: Synthetic peptide corresponding to C-SANGKNGDSAERGKE, from OTUD7A, at the internal region of the protein (NP_570971.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Related Product Information for anti-OTUD7A antibody

Has deubiquitinating activity that is directed towards 'Lys-48' or 'Lys-63'-linked polyubiquitin chains. Hydrolyzes both linear and branched forms of polyubiquitin.

Product Categories/Family for anti-OTUD7A antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 18702331
• NCBI GeneID: 161725
• NCBI Accession #: NP_570971.1
• NCBI GenBank Nucleotide #: NM_130901.1
• UniProt Accession #: Q8TE49; Q8IWK5
• Molecular Weight: 100,677 Da
• NCBI Official Full Name: OTU domain-containing protein 7A
• NCBI Official Synonym Full Names: OTU domain containing 7A
• NCBI Official Symbol: OTUD7A
• NCBI Official Synonym Symbols: OTUD7; C15orf16; C16ORF15; CEZANNE2
• NCBI Protein Information: OTU domain-containing protein 7A; cezanne 2; zinc finger protein Cezanne 2
• UniProt Protein Name: OTU domain-containing protein 7A
• Protein Family: OTU domain-containing protein
• UniProt Gene Name: OTUD7A
• UniProt Synonym Gene Names: C15orf16; CEZANNE2; OTUD7
• UniProt Entry Name: OTU7A_HUMAN

NCBI Description

Deubiquitinating enzymes (DUBs; see MIM 603478) are proteases that specifically cleave ubiquitin (MIM 191339) linkages, negating the action of ubiquitin ligases. OTUD7A belongs to a DUB subfamily characterized by an ovarian tumor (OTU) domain.[supplied by OMIM, May 2008]

Uniprot Description

Function: Has deubiquitinating activity towards 'Lys-11'-linked polyubiquitin chains. Ref.3 Ref.4

Catalytic activity: Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal). Ref.4

Subcellular location: Cytoplasm

By similarity. Nucleus

By similarity.

Sequence similarities: Belongs to the peptidase C64 family.Contains 1 A20-type zinc finger.Contains 1 OTU domain.