Rabbit anti-Human OSTM1 Polyclonal Antibody | anti-OSTM1 antibody

OSTM1, CT (OSTM1, GL, Osteopetrosis-associated transmembrane protein 1, Chloride channel 7 beta subunit) (FITC)

Cat. Num. AAA6329793

• Gene Names: OSTM1; GL; GIPN; OPTB5; HSPC019
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OSTM1; Polyclonal Antibody; CT (OSTM1; GL; Osteopetrosis-associated transmembrane protein 1; Chloride channel 7 beta subunit) (FITC); Chloride channel 7 beta subunit; anti-OSTM1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-OSTM1 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OSTM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-321 amino acids from the C-terminal region of human OSTM1.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OSTM1 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the OSTM1 Antibody detected the OSTM1 protein (arrow).)

Related Product Information for anti-OSTM1 antibody

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.

Product Categories/Family for anti-OSTM1 antibody

Antibodies; Transmembrane Proteins

References

Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009). Mazzolari, E., et al. Am. J. Hematol. 84(8):473-479(2009). Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008). Feigin, M.E., et al. Cell. Signal. 20(5):949-957(2008). Maranda, B., et al. J. Bone Miner. Res. 23(2):296-300(2008).

NCBI and Uniprot Product Information

• NCBI GI #: 30025026
• NCBI GeneID: 28962
• NCBI Accession #: NP_054747.2
• NCBI GenBank Nucleotide #: NM_014028.3
• UniProt Accession #: Q86WC4; Q5R391; Q6PCA7; Q7RTW6; Q8NC29; Q8TC82; Q9Y2S9; E1P5E3
• Molecular Weight: 37,257 Da
• NCBI Official Full Name: osteopetrosis-associated transmembrane protein 1
• NCBI Official Synonym Full Names: osteopetrosis associated transmembrane protein 1
• NCBI Official Symbol: OSTM1
• NCBI Official Synonym Symbols: GL; GIPN; OPTB5; HSPC019
• NCBI Protein Information: osteopetrosis-associated transmembrane protein 1
• UniProt Protein Name: Osteopetrosis-associated transmembrane protein 1
• Protein Family: Osteopetrosis-associated transmembrane protein
• UniProt Gene Name: OSTM1
• UniProt Synonym Gene Names: GL
• UniProt Entry Name: OSTM1_HUMAN

NCBI Description

This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008]