Western Blot (WB)
(Western blot analysis of osterix in lysates of 293T, using osterix Antibody.)
Rabbit Osterix Polyclonal Antibody | anti-OSX antibody
Osterix Antibody
Gene Names
SP7; OSX; OI11; OI12; osterix
Reactivity
Human, Mouse, RatPredicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus
Applications
Western Blot, ELISA
Purity
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Synonyms
Osterix; Polyclonal Antibody; Osterix Antibody; MGC126598; Sp 7; SP7; Sp7 transcription factor; SP7_HUMAN; Transcription factor Sp7; Zinc finger protein osterix; anti-OSX antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus
Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus
Clonality
Polyclonal
Isotype
IgG
Specificity
osterix Antibody detects endogenous levels of osterix.
Purity/Purification
The antiserum was purified by peptide affinity chromatography using SulfoLink Coupling Resin (Thermo Fisher Scientific).
Form/Format
Liquid; Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1mg/ml (varies by lot)
Sequence Length
431
Applicable Applications for anti-OSX antibody
Western Blot (WB), Peptide ELISA (EIA)
Application Notes
WB: 1:500-1:2000
ELISA (Peptide): 1:20000-1:40000
ELISA (Peptide): 1:20000-1:40000
Immunogen
A synthesized peptide derived from human osterix.
Tissue Specificity
Restricted to bone-derived cell.
Subcellular Location
Nucleus
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot analysis of osterix in lysates of 293T, using osterix Antibody.)
Western Blot (WB)
(Western blot analysis of osterix in lysates of 293T, using osterix Antibody.)
Related Product Information for anti-OSX antibody
Description: Transcriptional activator essential for osteoblast differentiation (PubMed:23457570). Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences (By similarity).
Post Translational Modifications: Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours.
Subunit Structure: Interacts with RIOX1; the interaction is direct and inhibits transcription activator activity.
Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family.
Post Translational Modifications: Ubiquitination at leads to proteasomal degradation. SP7 is a short-live protein with an endogenous half-life of approximately 12 hours.
Subunit Structure: Interacts with RIOX1; the interaction is direct and inhibits transcription activator activity.
Similarity: Belongs to the Sp1 C2H2-type zinc-finger protein family.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
Observed: 46 kDa
Predicted: 45 kDa
Predicted: 45 kDa
NCBI Official Full Name
transcription factor Sp7 isoform a
NCBI Official Synonym Full Names
Sp7 transcription factor
NCBI Official Symbol
SP7
NCBI Official Synonym Symbols
OSX; OI11; OI12; osterix
NCBI Protein Information
transcription factor Sp7
UniProt Protein Name
Transcription factor Sp7
UniProt Gene Name
SP7
UniProt Synonym Gene Names
OSX
NCBI Description
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein is a bone specific transcription factor and is required for osteoblast differentiation and bone formation.[provided by RefSeq, Jul 2010]
Uniprot Description
Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences ().
Research Articles on OSX
Similar Products
Product Notes
The OSX sp7 (Catalog #AAA9610868) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Osterix Antibody reacts with Human, Mouse, Rat Predicted: Pig, Zebrafish, Bovine, Horse, Rabbit, Dog, Xenopus and may cross-react with other species as described in the data sheet. AAA Biotech's Osterix can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Peptide ELISA (EIA). WB: 1:500-1:2000 ELISA (Peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the OSX sp7 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Osterix, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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