Rabbit OSA Polyclonal Antibody | anti-OSA antibody

Rabbit anti-Drosophila melanogaster (Fruit fly) OSA Polyclonal Antibody

• Gene Names: osa; anon-WO0118547.314; anon-WO0172774.126; C819; CG7467; DmelCG7467; E(E2F)3C; eld; en(lz)4F/4H; eyelid; l(3)00090; l(3)04539; l(3)j9C3; Osa; OSA; p300
• Reactivity: Drosophila melanogaster (Fruit fly)
• Applications: ELISA, Western Blot
• Purity: Protein A/G
• Synonyms: OSA; Polyclonal Antibody; Rabbit anti-Drosophila melanogaster (Fruit fly) OSA Polyclonal Antibody; OSA Antibody; Trithorax group protein osa; Protein eyelid; osa eld CG7467; anti-OSA antibody

• Host: Rabbit
• Reactivity: Drosophila melanogaster (Fruit fly)
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Protein A/G
• Form/Format: Liquid; Preservative: 0.03% Proclin 300; Constituents: 50% Glycerol, 0.01M PBS, pH7.4

• Applicable Applications for anti-OSA antibody: ELISA (EIA), WB (Western Blot) (ensure identification of antigen)
• Immunogen: Recombinant Drosophila melanogaster (Fruit fly) osa protein
• Conjugation: Non-conjugate
• Modification: Unmodified
• Deliverables: 1. 200ug recombinant immunogen protein/peptide (positive control).; 2. 1mL preimmune serum (negative control); 3. 10mg rabbit polyclonal antibody purified by Protein A/G.
• Quality Guarantee: 1. Antibody purity >90% confirmed by SDS-PAGE.; 2. Antibody titer > 1: 64,000 confirmed by ELISA; 3. Western Blot positive for the immunogen protein (Not applicable for synthetic peptide).
• Complementary Antibody: Customer can choose 1 FREE antibody from the list below. Please specify the catalog # when order:; * 6*His Monoclonal Antibody #MBS1491670; * DYKDDDDK tag Monoclonal Antibody #MBS1493946; * GAPDH Monoclonal Antibody #MBS1495524; * GFP Monoclonal Antibody #MBS1496050; * Myc tag Monoclonal Antibody #MBS1497694; * GST Monoclonal Antibody #MBS1497871; * Sumo tag Monoclonal Antibody #MBS1498878; * Goat Anti-Rabbit IgG (H+L) Antibody; HRP conjugated #MBS7053510; * HA-Tag Monoclonal Antibody #MBS7135631; * E-Tag Monoclonal Antibody #MBS7135632; * TUBA1A Monoclonal Antibody #MBS7135645; * TUBB Monoclonal Antibody #MBS9018332
• Preparation and Storage: Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

NCBI and Uniprot Product Information

• NCBI GI #: 281361984
• NCBI GeneID: 42130
• NCBI Accession #: NP_001163639.1
• NCBI GenBank Nucleotide #: NM_001170168.2
• UniProt Accession #: Q8IN94; O61603; Q9VEG7
• Molecular Weight: 284,064 Da
• NCBI Official Full Name: osa, isoform D
• NCBI Official Symbol: osa
• NCBI Official Synonym Symbols: anon-WO0118547.314; anon-WO0172774.126; C819; CG7467; DmelCG7467; E(E2F)3C; eld; en(lz)4F/4H; eyelid; l(3)00090; l(3)04539; l(3)j9C3; Osa; OSA; p300
• NCBI Protein Information: CG7467 gene product from transcript CG7467-RE
• UniProt Protein Name: Trithorax group protein osa
• Protein Family: Protein
• UniProt Gene Name: osa
• UniProt Synonym Gene Names: eld

Uniprot Description

Trithorax group (trxG) protein required for embryonic segmentation, development of the notum and wing margin, and photoreceptor differentiation. Required for the activation of genes such as Antp, Ubx and Eve. Binds to DNA without specific affinity, suggesting that it is recruited to promoters by promoter-specific proteins. Essential component of the Brahma complex, a multiprotein complex which is the equivalent of the yeast SWI/SNF complex and acts by remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. This complex can both serve as a transcriptional coactivator or corepressor, depending on the context. Acts as an essential coactivator for Zeste, which recruits the whole complex to specific genes. In contrast, it acts as a corepressor for Wg target genes, possibly via an interaction with Pan and Gro. It also acts as a negative regulator for proneural achaete-scute, when it is directly recruited by Pan and Chi. Also represses E2f activation.