Goat ORP7/OSBPL7 Polyclonal Antibody | anti-OSBPL7 antibody

Goat anti-ORP7/OSBPL7 Antibody

Cat. Num. AAA421482

• Gene Names: OSBPL7; ORP7
• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
• Applications: ELISA
• Purity: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Synonyms: ORP7/OSBPL7; Polyclonal Antibody; Goat anti-ORP7/OSBPL7 Antibody; OSBPL7; ORP7; FLJ20260; oxysterol binding protein-like 7; OSBP-related protein 7; oxysterol-binding protein-related protein 7; MGC71150; oxysterol-binding protein-like protein 7; OSBPL7 antibody; ORP7 antibody; FLJ20260 antibody; oxysterol binding protein-like 7 antibody; OSBP-related protein 7 antibody; oxysterol-binding protein-related protein 7 antibody; MGC71150 antibody; oxysterol-binding protein-like protein 7 antibody; ORP7 / OSBPL7; anti-OSBPL7 antibody

• Host: Goat
• Reactivity: Expected from sequence similarity: Human, Mouse, Rat, Dog, Pig, Cow
• Clonality: Polyclonal
• Purity/Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• Form/Format: Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
• Concentration: 100ug specific antibody in 200ul (varies by lot)
• Sequence: EPGYGNMDGAVLW
• Sequence Length: 842

• Applicable Applications for anti-OSBPL7 antibody: Peptide ELISA (EIA)
• Application Notes: Peptide ELISA: Antibody detection limit dilution 1: 32000.; Western Blot: Preliminary experiments gave bands at approx 40kDa in both Jurkat and Mouse Spleen extracts at 1ug/ml. Please note that currently we cannot find an explanation in the literature for these bands we observe given the predicted size of approx.97Kda according to NP_060201 and NP_665741.
• Immunogen: Peptide with sequence C-EPGYGNMDGAVLW, from the C Terminus of the protein sequence according to NP_665741.1.
• Epitope: C Terminus
• Preparation and Storage: Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

• NCBI GI #: 22035616
• NCBI GeneID: 114881
• NCBI Accession #: NP_665741.1
• NCBI GenBank Nucleotide #: NM_145798.2
• Molecular Weight: 40,186 Da
• NCBI Official Full Name: oxysterol-binding protein-related protein 7
• NCBI Official Synonym Full Names: oxysterol binding protein like 7
• NCBI Official Symbol: OSBPL7
• NCBI Official Synonym Symbols: ORP7
• NCBI Protein Information: oxysterol-binding protein-related protein 7
• UniProt Protein Name: Oxysterol-binding protein-related protein 7
• Protein Family: Oxysterol-binding protein-related protein
• UniProt Gene Name: OSBPL7
• UniProt Synonym Gene Names: ORP7; ORP-7; OSBP-related protein 7
• UniProt Entry Name: OSBL7_HUMAN

NCBI Description

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]

Uniprot Description

OSBPL7: a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. Two transcript variants encoding the same isoform have been identified. [provided by RefSeq, Jul 2008]

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: autophagic vacuole; cytosol; endoplasmic reticulum membrane; plasma membrane

Molecular Function: cholesterol binding; protein binding

Biological Process: lipid transport