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Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/20. )

Rabbit ORMDL3 Polyclonal Antibody | anti-ORMDL3 antibody

ORMDL3 Antibody

Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
ORMDL3; Polyclonal Antibody; ORMDL3 Antibody; ORM1-like 3;ORM1-like protein 3; ORML3; anti-ORMDL3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Applicable Applications for anti-ORMDL3 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-1:100
Immunogen
Full length fusion protein
Immunogen Species
Human
Conjugate
Non-conjugated
Preparation and Storage
Upon receipt, store at -20 degree C or -80 degree C. Avoid repeated freeze.

Immunohistochemistry (IHC)

(Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/20. )

Immunohistochemistry (IHC) (Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using at dilution 1/20. )
Product Categories/Family for anti-ORMDL3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15,689 Da
NCBI Official Full Name
ORM1-like protein 3
NCBI Official Synonym Full Names
ORMDL sphingolipid biosynthesis regulator 3
NCBI Official Symbol
ORMDL3
NCBI Protein Information
ORM1-like protein 3
UniProt Protein Name
ORM1-like protein 3
Protein Family
UniProt Gene Name
ORMDL3
UniProt Entry Name
ORML3_HUMAN

Uniprot Description

ORMDL3: Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling. Genetic variations in ORMDL3 are associated with susceptibility to asthma (ASTHMA). The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi. Belongs to the ORM family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: endoplasmic reticulum membrane; endoplasmic reticulum; integral to membrane

Molecular Function: protein binding

Biological Process: ceramide metabolic process

Research Articles on ORMDL3

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Product Notes

The ORMDL3 ormdl3 (Catalog #AAA7131858) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ORMDL3 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ORMDL3 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:50-1:100. Researchers should empirically determine the suitability of the ORMDL3 ormdl3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ORMDL3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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