Rabbit anti-Human OR2W5 Polyclonal Antibody | anti-OR2W5 antibody

OR2W5, CT (OR2W5, OR2W5P, Putative olfactory receptor 2W5) (PE)

Cat. Num. AAA6328601

• Gene Names: OR2W5; OR2W5P; OST722
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR2W5; Polyclonal Antibody; CT (OR2W5; OR2W5P; Putative olfactory receptor 2W5) (PE); Putative olfactory receptor 2W5; anti-OR2W5 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-OR2W5 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OR2W5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 282-311 amino acids from the C-terminal region of human OR2W5.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(OR2W5 Antibody (C-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the OR2W5 antibody detected the OR2W5 protein (arrow).)

Related Product Information for anti-OR2W5 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene has a coding sequence that is comparable in length to other olfactory receptor genes, but it should be noted that a frameshift is present in the 3' coding region that disrupts the 7-transmembrane domain structure in the protein. It is unclear if the protein can function as an olfactory receptor or if an alternate function is served. For this reason, this gene has also been interpreted to be a pseudogene.

Product Categories/Family for anti-OR2W5 antibody

Antibodies; Receptors; Olfactory

References

Fuchs, T., et al. Genomics 80(3):295-302(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 52317225
• NCBI GeneID: 441932
• NCBI Accession #: NP_001004698.1
• NCBI GenBank Nucleotide #: NM_001004698.2
• UniProt Accession #: A6NFC9; B9EH85
• Molecular Weight: 35,528 Da
• NCBI Official Full Name: putative olfactory receptor 2W5
• NCBI Official Synonym Full Names: olfactory receptor family 2 subfamily W member 5 (gene/pseudogene)
• NCBI Official Symbol: OR2W5
• NCBI Official Synonym Symbols: OR2W5P; OST722
• NCBI Protein Information: putative olfactory receptor 2W5
• UniProt Protein Name: Putative olfactory receptor 2W5
• Protein Family: Putative olfactory receptor
• UniProt Gene Name: OR2W5
• UniProt Synonym Gene Names: OR2W5P

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene has a coding sequence that is comparable in length to other olfactory receptor genes, but it should be noted that a frameshift is present in the 3' coding region that disrupts the 7-transmembrane domain structure in the protein. It is unclear if the protein can function as an olfactory receptor or if an alternate function is served. For this reason, this gene has also been interpreted to be a pseudogene. [provided by RefSeq, Jan 2010]

Uniprot Description

OR2W5: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: integral component of membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity

Biological Process: detection of chemical stimulus involved in sensory perception of smell; G-protein coupled receptor signaling pathway; sensory perception of smell