Rabbit anti-Human OR2M3 Polyclonal Antibody | anti-OR2M3 antibody

OR2M3, CT (OR2M3, OR2M3P, OR2M6, Olfactory receptor 2M3, Olfactory receptor 2M6, Olfactory receptor OR1-54) (PE)

Cat. Num. AAA6328469

• Gene Names: OR2M3; OR2M6; OR1-54; OR2M3P; OST003
• Reactivity: Human
• Applications: Flow Cytometry, Functional Assay, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR2M3; Polyclonal Antibody; CT (OR2M3; OR2M3P; OR2M6; Olfactory receptor 2M3; Olfactory receptor 2M6; Olfactory receptor OR1-54) (PE); Olfactory receptor OR1-54; anti-OR2M3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with R-Phycoerythrin (PE).

• Applicable Applications for anti-OR2M3 antibody: Flow Cytometry (FC/FACS), FLISA, Western Blot (WB)
• Application Notes: FC/FACS: 1:10-50; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: OR2M3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 247-276 amino acids from the C-terminal region of human OR2M3.
• Conjugate: PE
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: PE conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(OR2M3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the OR2M3 antibody detected the OR2M3 protein (arrow).)

Flow Cytometry (FC/FACS)

(OR2M3 Antibody (C-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)

Related Product Information for anti-OR2M3 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR2M3 antibody

Antibodies; Receptors; Olfactory

References

Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Fuchs, T., et al. Genomics 80(3):295-302(2002).

NCBI and Uniprot Product Information

• NCBI GI #: 52317200
• NCBI GeneID: 127062
• NCBI Accession #: NP_001004689.1
• NCBI GenBank Nucleotide #: NM_001004689.1
• UniProt Accession #: Q8NG83; Q6IEY0; B9EH06
• Molecular Weight: 34,827 Da
• NCBI Official Full Name: olfactory receptor 2M3
• NCBI Official Synonym Full Names: olfactory receptor, family 2, subfamily M, member 3
• NCBI Official Symbol: OR2M3
• NCBI Official Synonym Symbols: OR2M6; OR1-54; OR2M3P; OST003
• NCBI Protein Information: olfactory receptor 2M3; olfactory receptor 2M6; olfactory receptor OR1-54; olfactory receptor, family 2, subfamily M, member 6; novel 7 transmembrane receptor (rhodopsin family) protein; olfactory receptor, family 2, subfamily M, member 3 pseudogene
• UniProt Protein Name: Olfactory receptor 2M3
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR2M3
• UniProt Synonym Gene Names: OR2M3P; OR2M6
• UniProt Entry Name: OR2M3_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR2M3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1q44

Cellular Component: plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell