Rabbit anti-Human OR1D2 Polyclonal Antibody | anti-OR1D2 antibody

OR1D2, CT (OR1D2, OLFR1, Olfactory receptor 1D2, Olfactory receptor 17-4, Olfactory receptor OR17-6, Olfactory receptor-like protein HGMP07E) (AP)

Cat. Num. AAA6328162

• Gene Names: OR1D2; OLFR1; OR17-4
• Reactivity: Human
• Applications: Western Blot, ELISA
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR1D2; Polyclonal Antibody; CT (OR1D2; OLFR1; Olfactory receptor 1D2; Olfactory receptor 17-4; Olfactory receptor OR17-6; Olfactory receptor-like protein HGMP07E) (AP); Olfactory receptor-like protein HGMP07E; anti-OR1D2 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phosphatase (AP).

• Applicable Applications for anti-OR1D2 antibody: Western Blot (WB), ELISA (EIA)
• Application Notes: WB: 1:100-500; ELISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OR1D2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 285-312 amino acids from the C-terminal region of human OR1D2.
• Conjugate: AP
• Note: Preservative Free
• Preparation and Storage: Store product at 4 degree C. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.

Western Blot (WB)

(OR1D2 Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the OR1D2 antibody detected the OR1D2 protein (arrow).)

Related Product Information for anti-OR1D2 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR1D2 antibody

Antibodies; Receptors; Olfactory

References

Neuhaus, E.M., et al. J. Cell. Sci. 119 (PT 15), 3047-3056 (2006): Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Spehr, M., et al. Science 299(5615):2054-2058(2003). Fuchs, T., et al. Genomics 80(3):295-302(2002). Glusman, G., et al. Genomics 63(2):227-245(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 289547582
• NCBI GeneID: 4991
• NCBI Accession #: NP_002539.2
• NCBI GenBank Nucleotide #: NM_002548.2
• UniProt Accession #: P34982; Q6IFL8; Q96RA4; Q9UM78
• Molecular Weight: 35,240 Da
• NCBI Official Full Name: olfactory receptor 1D2
• NCBI Official Synonym Full Names: olfactory receptor, family 1, subfamily D, member 2
• NCBI Official Symbol: OR1D2
• NCBI Official Synonym Symbols: OLFR1; OR17-4
• NCBI Protein Information: olfactory receptor 1D2; olfactory receptor 17-4; olfactory receptor OR17-6; olfactory receptor-like protein HGMP07E
• UniProt Protein Name: Olfactory receptor 1D2
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR1D2
• UniProt Synonym Gene Names: OLFR1; OR17-4
• UniProt Entry Name: OR1D2_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR1D2: Odorant receptor which may be involved in sperm chemotaxis. Bourgeonal is a strong chemoattractant for sperm in vitro and is shown to be a strong agonist for OR1D2 in vitro. May also function in olfactory reception. Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 17p13.3

Cellular Component: integral to plasma membrane; plasma membrane; integral to membrane

Molecular Function: G-protein coupled receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; protein import into nucleus, translocation; single fertilization; sensory perception of smell; detection of chemical stimulus involved in sensory perception of smell; chemotaxis; cell motility