Rabbit anti-Human OR12D3 Polyclonal Antibody | anti-OR12D3 antibody

OR12D3, CT (OR12D3, Olfactory receptor 12D3, Hs6M1-27, Olfactory receptor OR6-27) (FITC)

Cat. Num. AAA6328088

• Gene Names: OR12D3; hs6M1-27
• Reactivity: Human
• Applications: Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OR12D3; Polyclonal Antibody; CT (OR12D3; Olfactory receptor 12D3; Hs6M1-27; Olfactory receptor OR6-27) (FITC); Olfactory receptor OR6-27; anti-OR12D3 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-OR12D3 antibody: Western Blot (WB), FLISA
• Application Notes: WB: 1:100-500; FLISA: 1:1,000; Applications are based on unconjugated antibody.
• Immunogen: OR12D3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 286-313 amino acids from the C-terminal region of human OR12D3.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OR12D3 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the OR12D3 Antibody detected the OR12D3 protein (arrow).)

Related Product Information for anti-OR12D3 antibody

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

Product Categories/Family for anti-OR12D3 antibody

Antibodies; Receptors; Olfactory

References

McElroy, J.P., et al. Hum. Mol. Genet. 19(15):3080-3088(2010). Pelak, K., et al. J. Infect. Dis. 201(8):1141-1149(2010). Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009): Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004). Mungall, A.J., et al. Nature 425(6960):805-811(2003).

NCBI and Uniprot Product Information

• NCBI GI #: 13624335
• NCBI GeneID: 81797
• NCBI Accession #: NP_112221.1
• NCBI GenBank Nucleotide #: NM_030959.2
• UniProt Accession #: Q9UGF7; Q5SQI8; Q6IF23; A2BDZ1
• Molecular Weight: 35,791 Da
• NCBI Official Full Name: olfactory receptor 12D3
• NCBI Official Synonym Full Names: olfactory receptor, family 12, subfamily D, member 3
• NCBI Official Symbol: OR12D3
• NCBI Official Synonym Symbols: hs6M1-27
• NCBI Protein Information: olfactory receptor 12D3; olfactory receptor OR6-27
• UniProt Protein Name: Olfactory receptor 12D3
• Protein Family: Olfactory receptor
• UniProt Gene Name: OR12D3
• UniProt Entry Name: O12D3_HUMAN

NCBI Description

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]

Uniprot Description

OR12D3: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Receptor, GPCR; GPCR, family 1

Chromosomal Location of Human Ortholog: 6p22.1

Cellular Component: integral to membrane; plasma membrane

Molecular Function: G-protein coupled receptor activity; transmembrane receptor activity; olfactory receptor activity

Biological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception; detection of chemical stimulus involved in sensory perception of smell