Rabbit Opioid Receptor, delta Polyclonal Antibody | anti-OPRD1 antibody

Opioid Receptor, delta (OPRD1,Opioid Receptor, Delta, Delta-type Opioid Receptor, DOR-1, OPRD)

Cat. Num. AAA630393

• Gene Names: OPRD1; OPRD
• Applications: ELISA, Western Blot, Immunocytochemistry
• Purity: Serum; Serum
• Synonyms: Opioid Receptor; delta; Polyclonal Antibody; delta (OPRD1; Delta; Delta-type Opioid Receptor; DOR-1; OPRD); Anti -Opioid Receptor; anti-OPRD1 antibody

• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Recognizes delta Opioid Receptor (360-372) and the reactivity of Delta Opioid Receptor is 60%. Does not react to Mu Opioid Receptor (391-398), Mu Opioid Receptor, Kappa Opioid Receptor (346-380) and Kappa Opioid Receptor. Specific for the COOH terminal of the delta opioid receptor.
• Purity/Purification: Serum; Serum
• Form/Format: Supplied as a lyophilized powder. Reconstitution with 0.1ml of 10mg/ml BSA in PBS.

• Applicable Applications for anti-OPRD1 antibody: ELISA (EL/EIA), Western Blot (WB), Immunocytochemistry (ICC)
• Application Notes: Suitable for use in ELISA, Western Blot and Immunocytochemistry.; Dilution: Western Blot: 1:800; Immunocytochemistry: 1:800
• Immunogen: Peptide analog of the carboxyl terminal of the delta opioid receptor covalently attached onto a carrier protein.
• Preparation and Storage: Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Product Categories/Family for anti-OPRD1 antibody

Antibodies; Abs to Opioid Receptors; Agonists

NCBI and Uniprot Product Information

• NCBI GI #: 119628077
• NCBI GeneID: 4985
• UniProt Accession #: P41143; B5B0B8
• Molecular Weight: 40,369 Da
• NCBI Official Full Name: opioid receptor, delta 1
• NCBI Official Synonym Full Names: opioid receptor, delta 1
• NCBI Official Symbol: OPRD1
• NCBI Official Synonym Symbols: OPRD
• NCBI Protein Information: delta-type opioid receptor; DOR-1; D-OR-1; OTTHUMP00000003778; delta opioid receptor 1
• UniProt Protein Name: Delta-type opioid receptor
• Protein Family: Delta-type opioid receptor
• UniProt Gene Name: OPRD1
• UniProt Synonym Gene Names: OPRD
• UniProt Entry Name: OPRD_HUMAN

Uniprot Description

DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: Membrane protein, multi-pass; Receptor, GPCR; Membrane protein, integral; GPCR, family 1

Chromosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: postsynaptic membrane; neuron projection; integral to plasma membrane; cytoplasm; plasma membrane; nerve terminal; intrinsic to plasma membrane; vesicle; lipid raft

Molecular Function: neuropeptide binding; protein binding; opioid receptor activity

Biological Process: adult locomotory behavior; activation of CREB transcription factor; regulation of calcium ion transport; sensory perception of pain; positive regulation of peptidyl-serine phosphorylation; G-protein signaling, coupled to cyclic nucleotide second messenger; negative regulation of protein oligomerization; G-protein coupled receptor protein signaling pathway; synaptic transmission; regulation of mitochondrial membrane potential; neuropeptide signaling pathway; protein import into nucleus, translocation; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; G-protein signaling, adenylate cyclase inhibiting pathway; regulation of sensory perception of pain