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Testing Data

Rabbit anti-Human ODC1 Polyclonal Antibody | anti-ODC1 antibody

ODC1 Antibody

Gene Names
ODC1; ODC
Reactivity
Human
Applications
ELISA, Western Blot
Synonyms
ODC1; Polyclonal Antibody; ODC1 Antibody; anti-ODC1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Form/Format
Serum column containing 0.02% NaN3
Sequence Length
461
Applicable Applications for anti-ODC1 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
ELISA: 1:10,000-1:80,000
WB: 1:200-1,000
Preparation and Storage
Already reconstituted in 200ul sterile H2O. The antibody is stable for at least one year when stored at-20 degree C.

Testing Data

Testing Data
Related Product Information for anti-ODC1 antibody
Rabbit polyclonal ODC1 (1) antibody was aised against recombinant protein of human ODC1.
References
(1) Hogarty, M.D., Norris, M.D., Davis, K., et al. ODC1 is a critical determinant of MYCN oncogenesis and a therapeutic target in neuroblastoma.Cancer Res. 68 (23), 9735-9745 (2008).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,148 Da
NCBI Official Full Name
ornithine decarboxylase isoform 1
NCBI Official Synonym Full Names
ornithine decarboxylase 1
NCBI Official Symbol
ODC1
NCBI Official Synonym Symbols
ODC
NCBI Protein Information
ornithine decarboxylase
UniProt Protein Name
Ornithine decarboxylase
UniProt Gene Name
ODC1
UniProt Synonym Gene Names
ODC

NCBI Description

This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

Uniprot Description

Catalyzes the first and rate-limiting step of polyamine biosynthesis that converts ornithine into putrescine, which is the precursor for the polyamines, spermidine and spermine. Polyamines are essential for cell proliferation and are implicated in cellular processes, ranging from DNA replication to apoptosis.

Research Articles on ODC1

Similar Products

Product Notes

The ODC1 odc1 (Catalog #AAA854678) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ODC1 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's ODC1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). ELISA: 1:10,000-1:80,000 WB: 1:200-1,000. Researchers should empirically determine the suitability of the ODC1 odc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ODC1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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