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Testing Data (Primary: Anti- OCLN at 1/300 dilution)

Rabbit OCLN Polyclonal Antibody | anti-OCLN antibody

OCLN Polyclonal Antibody

Gene Names
Ocln; Ocl; AI503564
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig
Applications
Western Blot
Purity
affinity purified by Protein A
Synonyms
OCLN; Polyclonal Antibody; OCLN Polyclonal Antibody; Occludin; Occludin-1; Occludin1; Occludin 1; FLJ08163; BLCPMG; FLJ18079; FLJ77961; FLJ94056; MGC34277; OCLN_HUMAN; Tight junction protein occludin.?; anti-OCLN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig
Clonality
Polyclonal
Specificity
OCLN Polyclonal Antibody detects endogenous levels of OCLN protein.
Purity/Purification
affinity purified by Protein A
Form/Format
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Applicable Applications for anti-OCLN antibody
Western Blot (WB)
Application Notes
WB: 1:500-2000
Immunogen
KLH conjugated synthetic peptide derived from mouse OCLN:431-522/522
Preparation and Storage
Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Testing Data

(Primary: Anti- OCLN at 1/300 dilution)

Testing Data (Primary: Anti- OCLN at 1/300 dilution)
Related Product Information for anti-OCLN antibody
This gene encodes an integral membrane protein which is located at tight junctions. This protein may be involved in the formation and maintenance of the tight junction. The possibility of several alternatively spliced products has been suggested but the full nature of these products has not been described

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
59,000 Da
NCBI Official Full Name
occludin
NCBI Official Synonym Full Names
occludin
NCBI Official Symbol
Ocln
NCBI Official Synonym Symbols
Ocl; AI503564
NCBI Protein Information
occludin
UniProt Protein Name
Occludin
Protein Family
UniProt Gene Name
Ocln
UniProt Synonym Gene Names
Ocl
UniProt Entry Name
OCLN_MOUSE

Uniprot Description

occludin: May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. It is able to induce adhesion when expressed in cells lacking tight junctions. Interacts with TJP1/ZO1 and with VAPA. Localized at tight junctions of both epithelial and endothelial cells. Highly expressed in kidney. Not detected in testis. Belongs to the ELL/occludin family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, multi-pass; Membrane protein, integral; Cell adhesion; Motility/polarity/chemotaxis

Cellular Component: apical plasma membrane; apicolateral plasma membrane; cell junction; cell surface; cytoplasmic vesicle; cytosol; endocytic vesicle; integral to membrane; intercellular junction; membrane; plasma membrane; tight junction

Molecular Function: protein binding; protein domain specific binding; S-adenosylmethionine-dependent methyltransferase activity; thiopurine S-methyltransferase activity

Biological Process: intercellular junction assembly and maintenance; methylation; S-adenosylhomocysteine metabolic process; S-adenosylmethionine metabolic process

Research Articles on OCLN

Similar Products

Product Notes

The OCLN ocln (Catalog #AAA3015316) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OCLN Polyclonal Antibody reacts with Human, Mouse, Rat, Dog, Pig, Cow, Horse, Guinea Pig and may cross-react with other species as described in the data sheet. AAA Biotech's OCLN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-2000. Researchers should empirically determine the suitability of the OCLN ocln for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OCLN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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