Rabbit anti-Human, Mouse OAZ2 Polyclonal Antibody | anti-OAZ2 antibody

OAZ2, CT (OAZ2, Ornithine decarboxylase antizyme 2) (FITC)

Cat. Num. AAA6327483

• Gene Names: OAZ2; AZ2
• Reactivity: Human, Mouse
• Applications: Immunohistochemistry, Western Blot
• Purity: Purified by Protein A Affinity Chromatography.
• Synonyms: OAZ2; Polyclonal Antibody; CT (OAZ2; Ornithine decarboxylase antizyme 2) (FITC); Ornithine decarboxylase antizyme 2; anti-OAZ2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Purified by Protein A Affinity Chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).

• Applicable Applications for anti-OAZ2 antibody: Immunohistochemistry (IHC), FLISA, Western Blot (WB)
• Application Notes: IHC: 1:50-100; FLISA: 1:1,000; WB: 1:100-500; Applications are based on unconjugated antibody.
• Immunogen: OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 128-155 amino acids from the C-terminal region of human OAZ2.
• Conjugate: FITC
• Note: Preservative Free
• Special Handling: Light sensitive
• Preparation and Storage: Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(OAZ2 Antibody (C-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the OAZ2 antibody detected the OAZ2 protein (arrow).)

Immunohistochemistry (IHC)

(OAZ2 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the OAZ2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)

Related Product Information for anti-OAZ2 antibody

Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].

Product Categories/Family for anti-OAZ2 antibody

Antibodies; Enzymes; Decarboxylase

References

Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010). Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007): Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005): Chen, H., et al. J. Biol. Chem. 277(48):45957-45961(2002). Coffino, P. Proc. Natl. Acad. Sci. U.S.A. 97(9):4421-4423(2000).

NCBI and Uniprot Product Information

• NCBI GI #: 9845507
• NCBI GeneID: 4947
• NCBI Accession #: NP_002528.1
• NCBI GenBank Nucleotide #: NM_002537.3
• UniProt Accession #: O95190
• Molecular Weight: 21,011 Da
• NCBI Official Full Name: ornithine decarboxylase antizyme 2 isoform 1
• NCBI Official Synonym Full Names: ornithine decarboxylase antizyme 2
• NCBI Official Symbol: OAZ2
• NCBI Official Synonym Symbols: AZ2
• NCBI Protein Information: ornithine decarboxylase antizyme 2; ODC-Az 2
• UniProt Protein Name: Ornithine decarboxylase antizyme 2
• Protein Family: Ornithine decarboxylase antizyme
• UniProt Gene Name: OAZ2
• UniProt Synonym Gene Names: AZ2; ODC-Az 2
• UniProt Entry Name: OAZ2_HUMAN