Rabbit anti-Human, Mouse OASIS Polyclonal Antibody | anti-OASIS antibody
OASIS, CT (Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, cAMP-responsive Element-binding Protein 3-like Protein 1, Old Astrocyte Specifically-induced Substance, Processed Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, CR
ELISA: 1:1,000
Applications are based on unconjugated antibody.
Western Blot (WB)
(Western blot analysis of CREB3L1 Antibody (C-term) in mouse stomach tissue lysates (35ug/lane). CREB3L1 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC)
(Formalin-fixed and paraffin-embedded human prostate carcinoma with CREB3L1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(Flow cytometric analysis of hela cells using CREB3L1 Antibody (C-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
NCBI and Uniprot Product Information
Uniprot Description
CREB3L1: Transcription factor that acts during endoplasmic reticulum stress by activating unfolded protein response target genes. Specifically involved in ER-stress response in astrocytes in the central nervous system (By similartity). May play a role in gliosis. In vitro, binds to box-B element, cAMP response element (CRE) and CRE-like sequences, and activates transcription through box-B element but not through CRE. Belongs to the bZIP family. ATF subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Transcription factor
Chromosomal Location of Human Ortholog: 11p11.2
Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to membrane; nucleus
Molecular Function: chromatin binding; protein binding; sequence-specific DNA binding
Biological Process: multicellular organismal development; osteoblast differentiation; transcription from RNA polymerase II promoter; unfolded protein response
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Product Notes
The OASIS creb3l1 (Catalog #AAA6490918) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OASIS, CT (Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, cAMP-responsive Element-binding Protein 3-like Protein 1, Old Astrocyte Specifically-induced Substance, Processed Cyclic AMP-responsive Element-binding Protein 3-like Protein 1, CR reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's OASIS can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB: 1:50-1:100 ELISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the OASIS creb3l1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "OASIS, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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