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Western Blot (WB) (Western blotAll lanes: NYX antibody at 7.23 ug/mlLane 1: Mouse gonadal tissueLane 2: Mouse liver tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 52 kDaObserved band size: 52,37,45,90 kDa)

Rabbit anti-Human, Mouse NYX Polyclonal Antibody | anti-NYX antibody

NYX Antibody

Gene Names
NYX; CLRP; NBM1; CSNB1; CSNB4; CSNB1A
Reactivity
Human, Mouse
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Antigen Affinity Purified
Synonyms
NYX; Polyclonal Antibody; NYX Antibody; Nyctalopin; CLRP; anti-NYX antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purified
Form/Format
Liquid
Sequence Length
481
Applicable Applications for anti-NYX antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species
Human
Immunogen
Recombinant human Nyctalopin protein (C-200AA)
Conjugate
Non-conjugated
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-139163
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C or -80 degree C. Avoid repeated freeze.

Western Blot (WB)

(Western blotAll lanes: NYX antibody at 7.23 ug/mlLane 1: Mouse gonadal tissueLane 2: Mouse liver tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 52 kDaObserved band size: 52,37,45,90 kDa)

Western Blot (WB) (Western blotAll lanes: NYX antibody at 7.23 ug/mlLane 1: Mouse gonadal tissueLane 2: Mouse liver tissueSecondaryGoat polyclonal to rabbit IgG at 1/10000 dilutionPredicted band size: 52 kDaObserved band size: 52,37,45,90 kDa)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045534 at dilution 1:100)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded human kidney tissue using MBS7045534 at dilution 1:100)
Related Product Information for anti-NYX antibody
cytoplasm, intracellular, protein kinase inhibitor activity, cytokine-mediated signaling pathway, negative regulation of JAK-STAT cascade, negative regulation of protein kinase activity

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,000 Da
NCBI Official Full Name
nyctalopin
NCBI Official Synonym Full Names
nyctalopin
NCBI Official Symbol
NYX
NCBI Official Synonym Symbols
CLRP; NBM1; CSNB1; CSNB4; CSNB1A
NCBI Protein Information
nyctalopin
UniProt Protein Name
Nyctalopin
Protein Family
UniProt Gene Name
NYX
UniProt Synonym Gene Names
CLRP
UniProt Entry Name
NYX_HUMAN

NCBI Description

The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB. [provided by RefSeq, Oct 2008]

Uniprot Description

NYX: Defects in NYX are the cause of congenital stationary night blindness type 1A (CSNB1A); also called X- linked congenital stationary night blindness (XLCSNB). Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision. CSNB1A is characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class IV subfamily.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: Xp11.4

Cellular Component: cytoplasm; intracellular

Molecular Function: protein kinase inhibitor activity

Biological Process: cytokine and chemokine mediated signaling pathway; negative regulation of JAK-STAT cascade; negative regulation of protein kinase activity

Disease: Night Blindness, Congenital Stationary, Type 1a

Research Articles on NYX

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Product Notes

The NYX nyx (Catalog #AAA7045534) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NYX Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NYX can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the NYX nyx for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NYX, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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