Rabbit anti-Human NVL Polyclonal Antibody | anti-NVL antibody

NVL, CT (NVL, Nuclear valosin-containing protein-like)

Cat. Num. AAA644940

• Reactivity: Human
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: NVL; Polyclonal Antibody; CT (NVL; Nuclear valosin-containing protein-like); Anti -NVL; anti-NVL antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Human
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

• Applicable Applications for anti-NVL antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in Western Blot, ELISA; Dilution: ELISA: 1:1,000; Western Blot: 1:100-500
• Immunogen: NVL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 795-823 amino acids from the C-terminal region of human NVL.
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(NVL Antibody (C-term) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the NVL antibody detected the NVL protein (arrow).)

Product Categories/Family for anti-NVL antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 341865581
• NCBI GeneID: 4931
• NCBI Accession #: NP_001230076.1
• NCBI GenBank Nucleotide #: NM_001243147.1
• UniProt Accession #: O15381; Q96EM7; B4DMC4; B4DP98
• Molecular Weight: 95,051 Da
• NCBI Official Full Name: nuclear valosin-containing protein-like isoform 4
• NCBI Official Synonym Full Names: nuclear VCP-like
• NCBI Official Symbol: NVL
• NCBI Protein Information: nuclear valosin-containing protein-like; NVLp
• UniProt Protein Name: Nuclear valosin-containing protein-like
• Protein Family: Nuclear valosin-containing protein
• UniProt Gene Name: NVL
• UniProt Synonym Gene Names: NVLp
• UniProt Entry Name: NVL_HUMAN

NCBI Description

This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011]

Uniprot Description

NVL: a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin. [provided by RefSeq, Aug 2011]

Protein type: Nucleolus

Chromosomal Location of Human Ortholog: 1q41-q42.2

Cellular Component: mitochondrion; membrane; cytoplasm; plasma membrane; nucleolus; nucleus

Molecular Function: ATP binding