Western Blot (WB)
(NUP88 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NUP88 antibody detected the NUP88 protein (arrow).)
Rabbit NUP88 Polyclonal Antibody | anti-NUP88 antibody
NUP88 Antibody (C-term)
Western Blot (WB)
(NUP88 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NUP88 antibody detected the NUP88 protein (arrow).)
Western Blot (WB)
(NUP88 Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the NUP88 antibody detected the NUP88 protein (arrow).)
extends across the nuclear envelope, forming a gateway that
regulates the flow of macromolecules between the nucleus and the
cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the
main components of the nuclear pore complex in eukaryotic cells.
The protein encoded by this gene belongs to the nucleoporin family
and is associated with the oncogenic nucleoporin CAN/Nup214 in a
dynamic subcomplex. This protein is also overexpressed in a large
number of malignant neoplasms and precancerous dysplasias.
Brustmann, H., et al. Ann Diagn Pathol 13(5):303-307(2009)
Cheng, Y.T., et al. Plant Cell 21(8):2503-2516(2009)
Andres-Hernando, A., et al. J. Biol. Chem. 283(36):25082-25090(2008)
Kodiha, M., et al. Biochim. Biophys. Acta 1783(3):405-418(2008)
NCBI and Uniprot Product Information
NCBI Description
The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. [provided by RefSeq, Jul 2008]
Uniprot Description
NUP88: Essential component of nuclear pore complex.
Protein type: Nucleoporin; Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 17p13.2
Cellular Component: nucleoplasm; nuclear pore; cytosol
Molecular Function: transporter activity
Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; glucose transport; viral infectious cycle; protein transport; hexose transport; carbohydrate metabolic process; viral transcription; gene expression; mitotic cell cycle; transmembrane transport
Research Articles on NUP88
Similar Products
Product Notes
The NUP88 nup88 (Catalog #AAA9206815) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 701-730. The NUP88 Antibody (C-term) reacts with Human (Predicted Reactivity: Mouse, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's NUP88 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NUP88 nup88 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NUP88, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
