Rabbit NUCKS1 Polyclonal Antibody | anti-NUCKS1 antibody

NUCKS1 Rabbit Polyclonal

Cat. Num. AAA7602123

• Gene Names: NUCKS1; JC7; NUCKS
• Reactivity: Human, Mouse, Rat
• Applications: ELISA, Western Blot, Immunohistochemistry, Immunoprecipitation
• Purity: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Synonyms: NUCKS1; Polyclonal Antibody; NUCKS1 Rabbit Polyclonal; anti-NUCKS1 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: >=95% as determined by SDS-PAGE; Immunogen Affinity Purified
• Form/Format: Liquid
• Sequence Length: 243

• Applicable Applications for anti-NUCKS1 antibody: ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)
• Immunogen: Nuclear casein kinase and cyclin-dependent kinase substrate 1
• Preparation and Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20 degree C for 24 months (Avoid repeated freeze / thaw cycles.)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded human gliomas using MBS7602123 (NUCKS1 antibody) at dilution of 1:50)

Western Blot (WB)

(SGC-7901 cells were subjected to SDS PAGE followed by western blot with MBS7602123 (NUCKS1 antibody) at dilution of 1:400)

NCBI and Uniprot Product Information

• NCBI GI #: 56118310
• NCBI GeneID: 64710
• NCBI Accession #: NP_073568.2
• NCBI GenBank Nucleotide #: NM_022731.4
• Molecular Weight: 22,776 Da
• NCBI Official Full Name: nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
• NCBI Official Synonym Full Names: nuclear casein kinase and cyclin dependent kinase substrate 1
• NCBI Official Symbol: NUCKS1
• NCBI Official Synonym Symbols: JC7; NUCKS
• NCBI Protein Information: nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
• UniProt Protein Name: Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1
• Protein Family: Nuclear ubiquitous casein and cyclin-dependent kinase substrate
• UniProt Gene Name: NUCKS1
• UniProt Synonym Gene Names: NUCKS
• UniProt Entry Name: NUCKS_HUMAN

NCBI Description

This gene encodes a nuclear protein that is highly conserved in vertebrates. The conserved regions of the protein contain several consensus phosphorylation sites for casein kinase II and cyclin-dependent kinases, two putative nuclear localization signals, and a basic DNA-binding domain. It is phosphorylated in vivo by Cdk1 during mitosis of the cell cycle. [provided by RefSeq, Aug 2010]

Uniprot Description

NUCKS: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 1q32.1

Cellular Component: cytoplasm; nucleus

Biological Process: glucose homeostasis; positive regulation of insulin receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter