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Western Blot (WB) (NU188 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NU188 antibody detected the NU188 protein (arrow).)

Rabbit anti-Human NU188 Polyclonal Antibody | anti-NUP188 antibody

NU188 Antibody (N-term)

Gene Names
NUP188; hNup188; KIAA0169
Reactivity
Human
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NU188; Polyclonal Antibody; NU188 Antibody (N-term); Nucleoporin NUP188 homolog; hNup188; NUP188; KIAA0169; anti-NUP188 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NU188 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-160 amino acids from the N-terminal region of human NU188.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
132-160
Sequence Length
1,638
Applicable Applications for anti-NUP188 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(NU188 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NU188 antibody detected the NU188 protein (arrow).)

Western Blot (WB) (NU188 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NU188 antibody detected the NU188 protein (arrow).)
Related Product Information for anti-NUP188 antibody
NUP188 may function as a component of the nuclear pore complex (NPC).
References
Denoeud, F., et al. Genome Res. 17(6):746-759(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
Le Rouzic, E., et al. J. Biol. Chem. 277(47):45091-45098(2002)
Miller, B.R., et al. Mol. Biol. Cell 11(10):3381-3396(2000)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
196043
NCBI Official Full Name
nucleoporin NUP188 homolog
NCBI Official Synonym Full Names
nucleoporin 188kDa
NCBI Official Symbol
NUP188
NCBI Official Synonym Symbols
hNup188; KIAA0169
NCBI Protein Information
nucleoporin NUP188 homolog
UniProt Protein Name
Nucleoporin NUP188 homolog
Protein Family
UniProt Gene Name
NUP188
UniProt Synonym Gene Names
KIAA0169; hNup188
UniProt Entry Name
NU188_HUMAN

NCBI Description

The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013]

Uniprot Description

NUP188: May function as a component of the nuclear pore complex (NPC). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleoporin

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: membrane; nuclear pore; nuclear envelope

Biological Process: mRNA transport; viral reproduction; cytokine and chemokine mediated signaling pathway; mitotic nuclear envelope disassembly; pathogenesis; viral infectious cycle; glucose transport; protein transport; hexose transport; carbohydrate metabolic process; gene expression; viral transcription; mitotic cell cycle; transmembrane transport

Similar Products

Product Notes

The NUP188 nup188 (Catalog #AAA9204750) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 132-160. The NU188 Antibody (N-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NU188 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NUP188 nup188 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NU188, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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