Rabbit anti-Human, Mouse NTH1 Polyclonal Antibody
NTH1 (E. coli Endonuclease III Homologue)
Reactivity
Human, Mouse
Applications
ELISA
Purity
Affinity PurifiedPurified by affinity chromatography.
Synonyms
NTH1; Polyclonal Antibody; NTH1 (E. coli Endonuclease III Homologue); Anti -NTH1 (E. coli Endonuclease III Homologue); anti-NTH1 antibody
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
Specific for NTH1. Species crossreactivity: Reacts with human NTH1. There is sequence homology to mouse.
Purity/Purification
Affinity Purified
Purified by affinity chromatography.
Purified by affinity chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.05% sodium azide.
Applicable Applications for anti-NTH1 antibody
ELISA (EL/EIA)
Immunogen
A peptide derived from the human NTH1.
Positive Control
K562 cell extracts, Hela cell extracts.
Preparation and Storage
-20 degree C
Related Product Information for anti-NTH1 antibody
Oxygen radicals damage chromosonal DNA causing cell death and inducing mutations. Although a major focus of oxidatively damaged DNA has centered on the repair of 8-oxo-G, a number of other damaged DNA sites are created by free-radical attack on DNA. The human NTH1 repair protein is one enzyme that has been shown to act on a large number of these other oxidatively damaged DNA sites. A homologue of E. coli Endonuclease III, NTH is a DNA glycosylase with apurinic/apyrimidinic lyase activity. The NTH protein has broad substrate specificity, including numerous ring saturation and fragmentation products of pyrimidines. Research indicates NTH plays a crucial role in removal of oxidative base lesions in mitochondrial DNA.
Product Categories/Family for anti-NTH1 antibody
NCBI and Uniprot Product Information
Similar Products
Product Notes
The NTH1 (Catalog #AAA613782) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NTH1 (E. coli Endonuclease III Homologue) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NTH1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA). Researchers should empirically determine the suitability of the NTH1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NTH1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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