Western Blot (WB)
(NT5C2 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NT5C2 antibody detected the NT5C2 protein (arrow).)
Rabbit NT5C2 Polyclonal Antibody | anti-NT5C2 antibody
NT5C2 Antibody (N-term)
Western Blot (WB)
(NT5C2 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NT5C2 antibody detected the NT5C2 protein (arrow).)
Western Blot (WB)
(NT5C2 Antibody (N-term) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the NT5C2 antibody detected the NT5C2 protein (arrow).)
hydrolyzes inosine 5-prime-monophosphate (IMP) and other purine
nucleotides, and is allosterically activated by various compounds,
including ATP. The enzyme is exclusively located in the cytoplasmic
matrix of cells and may have a critical role in the maintenance of
a constant composition of intracellular purine/pyrimidine
nucleotides in cooperation with other nucleotidases.[supplied by
OMIM].
Yamauchi, T., et al. Biochem. Pharmacol. 77(12):1780-1786(2009)
Newton-Cheh, C., et al. Nat. Genet. (2009) In press :
Venkatesan, K., et al. Nat. Methods 6(1):83-90(2009)
Jordheim, L.P., et al. Drug Metab. Dispos. 36(12):2419-2423(2008)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a hydrolase that serves as an important role in cellular purine metabolism by acting primarily on inosine 5'-monophosphate and other purine nucleotides. [provided by RefSeq, Oct 2011]
Uniprot Description
NT5C2: May have a critical role in the maintenance of a constant composition of intracellular purine/pyrimidine nucleotides in cooperation with other nucleotidases. Preferentially hydrolyzes inosine 5'-monophosphate (IMP) and other purine nucleotides. Belongs to the 5'(3')-deoxyribonucleotidase family.
Protein type: Nucleotide Metabolism - purine; Cofactor and Vitamin Metabolism - nicotinate and nicotinamide; Nucleotide Metabolism - pyrimidine; EC 3.1.3.5; Hydrolase
Chromosomal Location of Human Ortholog: 10q24.32
Cellular Component: cytosol
Molecular Function: 5'-nucleotidase activity; protein binding; metal ion binding; nucleoside phosphotransferase activity; nucleotide binding
Biological Process: dephosphorylation; nucleobase, nucleoside and nucleotide metabolic process; IMP metabolic process; purine nucleotide catabolic process; adenosine metabolic process; drug metabolic process; phosphorylation; purine base metabolic process
Research Articles on NT5C2
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Product Notes
The NT5C2 nt5c2 (Catalog #AAA9212521) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 5-33. The NT5C2 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Mouse) and may cross-react with other species as described in the data sheet. AAA Biotech's NT5C2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NT5C2 nt5c2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NT5C2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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