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Western Blot (WB) (Western blot analysis of extracts of various cells, using NRGN antibody.)

Rabbit NRGN Polyclonal Antibody | anti-NRGN antibody

NRGN Polyclonal Antibody

Gene Names
NRGN; RC3; hng
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Purity
Antigen Affinity Purification
Synonyms
NRGN; Polyclonal Antibody; NRGN Polyclonal Antibody; RC3; hng; anti-NRGN antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen Affinity Purification
Sequence Length
78
Applicable Applications for anti-NRGN antibody
Western Blot (WB)
Application Notes
WB: 1:500 - 1:2000
Immunogen
Recombinant protein of human NRGN
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Santa Cruz Alternative
Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18336 / sc-50401
Preparation and Storage
Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of extracts of various cells, using NRGN antibody.)

Western Blot (WB) (Western blot analysis of extracts of various cells, using NRGN antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
8kDa
NCBI Official Full Name
neurogranin
NCBI Official Synonym Full Names
neurogranin
NCBI Official Symbol
NRGN
NCBI Official Synonym Symbols
RC3; hng
NCBI Protein Information
neurogranin
UniProt Protein Name
Neurogranin
Protein Family
UniProt Gene Name
NRGN
UniProt Synonym Gene Names
Ng
UniProt Entry Name
NEUG_HUMAN

NCBI Description

Neurogranin (NRGN) is the human homolog of the neuron-specific rat RC3/neurogranin gene. This gene encodes a postsynaptic protein kinase substrate that binds calmodulin in the absence of calcium. The NRGN gene contains four exons and three introns. The exons 1 and 2 encode the protein and exons 3 and 4 contain untranslated sequences. It is suggested that the NRGN is a direct target for thyroid hormone in human brain, and that control of expression of this gene could underlay many of the consequences of hypothyroidism on mental states during development as well as in adult subjects. [provided by RefSeq, Jul 2008]

Uniprot Description

neurogranin: Acts as a third messenger substrate of protein kinase C-mediated molecular cascades during synaptic development and remodeling. Binds to calmodulin in the absence of calcium. Belongs to the neurogranin family.

Protein type: Cell development/differentiation

Chromosomal Location of Human Ortholog: 11q24

Biological Process: nervous system development; signal transduction

Research Articles on NRGN

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Product Notes

The NRGN nrgn (Catalog #AAA2541339) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NRGN Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NRGN can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the NRGN nrgn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NRGN, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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