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Goat NRAP Polyclonal Antibody | anti-NRAP antibody

Goat anti-NRAP Antibody

Gene Names
NRAP; N-RAP
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
NRAP; Polyclonal Antibody; Goat anti-NRAP Antibody; Goat Anti-NRAP Antibody; nebulin-related anchoring protein; nebulin-related anchoring protein antibody; NRAP antibody; anti-NRAP antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
EDTKSQCHVSLD
Sequence Length
1695
Applicable Applications for anti-NRAP antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 4000.
Western Blot: Preliminary experiments in Human Heart, Skeletal Muscle and Uterus lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml).
Immunogen
Peptide with sequence EDTKSQCHVSLD, from the internal region of the protein sequence according to NP_006166.3; NP_932326.2.
Epitope
Internal region
Note
This antibody is expected to recognize all reported isoforms (NP_006166.3; NP_932326.2).
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
192,997 Da
NCBI Official Full Name
nebulin-related-anchoring protein isoform 1
NCBI Official Synonym Full Names
nebulin related anchoring protein
NCBI Official Symbol
NRAP
NCBI Official Synonym Symbols
N-RAP
NCBI Protein Information
nebulin-related-anchoring protein
UniProt Protein Name
Nebulin-related-anchoring protein
UniProt Gene Name
NRAP
UniProt Synonym Gene Names
N-RAP
UniProt Entry Name
NRAP_HUMAN

Uniprot Description

NRAP: May be involved in anchoring the terminal actin filaments in the myofibril to the membrane and in transmitting tension from the myofibrils to the extracellular matrix. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 10q24-q26

Cellular Component: fascia adherens; muscle tendon junction

Molecular Function: actin binding; muscle alpha-actinin binding; zinc ion binding

Research Articles on NRAP

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Product Notes

The NRAP nrap (Catalog #AAA422799) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-NRAP Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig and may cross-react with other species as described in the data sheet. AAA Biotech's NRAP can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 4000. Western Blot: Preliminary experiments in Human Heart, Skeletal Muscle and Uterus lysates gave no specific signal but low background (at antibody concentration up to 1ug/ml). Researchers should empirically determine the suitability of the NRAP nrap for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: EDTKSQCHVS LD. It is sometimes possible for the material contained within the vial of "NRAP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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