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Western Blot (WB) (All lanes : Anti-NPY2R Antibody (N-term) at 1:2000 dilutionLane 1: mouse brain lysatesLane 2: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 43 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Rabbit NPY2R Polyclonal Antibody | anti-NPY2R antibody

NPY2R Antibody (N-term)

Gene Names
NPY2R; NPY2-R
Reactivity
Human, mouse, rat
Applications
Western Blot, ELISA
Purity
Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NPY2R; Polyclonal Antibody; NPY2R Antibody (N-term); Neuropeptide Y receptor type 2; NPY2-R; NPY-Y2 receptor; Y2 receptor; anti-NPY2R antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, mouse, rat
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NPY2R antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 29-65 amino acids from the N-terminal region of human NPY2R.
Purity/Purification
Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Length
381
Applicable Applications for anti-NPY2R antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Crown Antibody
Yes
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(All lanes : Anti-NPY2R Antibody (N-term) at 1:2000 dilutionLane 1: mouse brain lysatesLane 2: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 43 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (All lanes : Anti-NPY2R Antibody (N-term) at 1:2000 dilutionLane 1: mouse brain lysatesLane 2: rat brain lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 43 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB)

(Anti-NPY2R Antibody (N-term) at 1:1000 dilution + human kidney lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 43 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)

Western Blot (WB) (Anti-NPY2R Antibody (N-term) at 1:1000 dilution + human kidney lysatesLysates/proteins at 20 ug per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilutionPredicted band size : 43 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Related Product Information for anti-NPY2R antibody
Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid.
Product Categories/Family for anti-NPY2R antibody
References
Gerald C.,et al.J. Biol. Chem. 270:26758-26761(1995).
Gehlert D.R.,et al.Mol. Pharmacol. 49:224-228(1996).
Rose P.M.,et al.J. Biol. Chem. 270:22661-22664(1995).
Yan H.,et al.Proc. Natl. Acad. Sci. U.S.A. 93:4661-4665(1996).
Ammar D.A.,et al.Genomics 38:392-398(1996).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42731
NCBI Official Full Name
neuropeptide Y receptor type 2
NCBI Official Synonym Full Names
neuropeptide Y receptor Y2
NCBI Official Symbol
NPY2R
NCBI Official Synonym Symbols
NPY2-R
NCBI Protein Information
neuropeptide Y receptor type 2
UniProt Protein Name
Neuropeptide Y receptor type 2
Protein Family
UniProt Gene Name
NPY2R
UniProt Synonym Gene Names
NPY2-R; Y2 receptor
UniProt Entry Name
NPY2R_HUMAN

Uniprot Description

NPY2R: Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is PYY > NPY > PYY (3-36) > NPY (2-36) > [Ile-31, Gln-34] PP > [Leu- 31, Pro-34] NPY > PP, [Pro-34] PYY and NPY free acid. Belongs to the G-protein coupled receptor 1 family.

Protein type: Receptor, GPCR; GPCR, family 1; Membrane protein, multi-pass; Membrane protein, integral

Chromosomal Location of Human Ortholog: 4q31

Cellular Component: integral to plasma membrane; nonmotile primary cilium; plasma membrane

Molecular Function: peptide YY receptor activity; protein binding; calcium channel regulator activity; neuropeptide Y receptor activity; receptor activity

Biological Process: positive regulation of dopamine secretion; secretion; behavioral fear response; positive regulation of cell adhesion; negative regulation of synaptic transmission, glutamatergic; positive regulation of peptide secretion; locomotory behavior; negative regulation of cAMP biosynthetic process; elevation of cytosolic calcium ion concentration; neuropeptide signaling pathway; negative regulation of secretion; regulation of sensory perception of pain; positive regulation of smooth muscle contraction; G-protein signaling, adenylate cyclase inhibiting pathway; positive regulation of circadian sleep/wake cycle, non-REM sleep; nitric oxide mediated signal transduction; negative regulation of neurological process

Research Articles on NPY2R

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Product Notes

The NPY2R npy2r (Catalog #AAA9205360) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPY2R Antibody (N-term) reacts with Human, mouse, rat and may cross-react with other species as described in the data sheet. AAA Biotech's NPY2R can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the NPY2R npy2r for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPY2R, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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