Rabbit anti-Human, Mouse NPNT Polyclonal Antibody | anti-NPNT antibody
NPNT Antibody
NCBI and Uniprot Product Information
Uniprot Description
NPNT: Functional ligand of integrin alpha-8/beta-1 in kidney development. Regulates the expression of GDNF with integrin alpha- 8/beta-1 which is essential for kidney development. May also play a role in the development and function of various tissues, regulating cell adhesion, spreading and survival through the binding of several integrins. Belongs to the nephronectin family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Secreted
Chromosomal Location of Human Ortholog: 4q24
Cellular Component: proteinaceous extracellular matrix; smooth muscle contractile fiber; extracellular region; basement membrane
Molecular Function: integrin binding; calcium ion binding
Biological Process: positive regulation of osteoblast differentiation; establishment of protein localization; extracellular matrix organization and biogenesis; ureteric bud development; ureteric bud branching; cell-matrix adhesion; cell-cell adhesion mediated by integrin; positive regulation of transforming growth factor beta receptor signaling pathway; positive regulation of smooth muscle contraction
Research Articles on NPNT
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Product Notes
The NPNT npnt (Catalog #AAA9629901) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NPNT Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NPNT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA)(peptide). ELISA(peptide): 1:20000-1:40000. Researchers should empirically determine the suitability of the NPNT npnt for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPNT, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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