Western Blot (WB)
(Western blot analysis of NPAS2 expression in HeLa (A), HepG2 (B) whole cell lysates.)
Rabbit NPAS2 Polyclonal Antibody | anti-NPAS2 antibody
Anti-NPAS2 Antibody
Western Blot (WB)
(Western blot analysis of NPAS2 expression in HeLa (A), HepG2 (B) whole cell lysates.)
Western Blot (WB)
(Western blot analysis of NPAS2 expression in HeLa (A), HepG2 (B) whole cell lysates.)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a member of the basic helix-loop-helix (bHLH)-PAS family of transcription factors. A similar mouse protein may play a regulatory role in the acquisition of specific types of memory. It also may function as a part of a molecular clock operative in the mammalian forebrain. [provided by RefSeq, Jul 2008]
Uniprot Description
NPAS2: BMAL1-NPAS2 heterodimers activate E-box element (5'- CACGTG-3') transcription of a number of proteins of the circadian clock. This transcription is inhibited in a feedback loop by PER, and also by CRY proteins.
Protein type: Transcription factor; DNA-binding
Chromosomal Location of Human Ortholog: 2q11.2
Cellular Component: transcription factor complex; nucleus; cytosol
Molecular Function: protein dimerization activity; signal transducer activity; protein binding; DNA binding; metal ion binding; Hsp90 protein binding; transcription factor activity
Biological Process: circadian rhythm; locomotor rhythm; circadian sleep/wake cycle; central nervous system development; positive regulation of DNA repair; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; positive regulation of transcription from RNA polymerase II promoter; response to redox state; circadian regulation of gene expression; cellular lipid metabolic process; signal transduction; response to DNA damage stimulus
Research Articles on NPAS2
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Product Notes
The NPAS2 npas2 (Catalog #AAA820533) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NPAS2 Antibody reacts with Human, Mouse, Rat, Monkey and may cross-react with other species as described in the data sheet. AAA Biotech's NPAS2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB (1/500 - 1/1000). Researchers should empirically determine the suitability of the NPAS2 npas2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NPAS2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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