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Western Blot (WB) (Western blot analysis of NP60 expression in Hela (A) whole cell lysates.)

Rabbit anti-Human NP60 Polyclonal Antibody | anti-NP60 antibody

Anti-NP60 Antibody

Gene Names
GLYR1; NP60; BM045; HIBDL; N-PAC
Reactivity
Human
Applications
Western Blot
Purity
Purified by immunogen affinity chromatography
Synonyms
NP60; Polyclonal Antibody; Anti-NP60 Antibody; HIBDL; Putative oxidoreductase GLYR1; 3-hydroxyisobutyrate dehydrogenase-like protein; Cytokine-like nuclear factor N-PAC; Glyoxylate reductase 1 homolog; Nuclear protein NP60; Nuclear protein of 60 kDa; anti-NP60 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of NP60 protein.
Purity/Purification
Purified by immunogen affinity chromatography
Form/Format
Liquid in 0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol, and 0.01% sodium azide.
Sequence Length
484
Applicable Applications for anti-NP60 antibody
Western Blot (WB)
Application Notes
WB: 1/500 - 1/2000
Immunogen
Recombinant full length protein of human NP60
Preparation and Storage
Shipped at 4 degree C. Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of NP60 expression in Hela (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of NP60 expression in Hela (A) whole cell lysates.)
Related Product Information for anti-NP60 antibody
Rabbit polyclonal antibody to NP60

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
52,559 Da
NCBI Official Full Name
putative oxidoreductase GLYR1 isoform 2
NCBI Official Synonym Full Names
glyoxylate reductase 1 homolog
NCBI Official Symbol
GLYR1
NCBI Official Synonym Symbols
NP60; BM045; HIBDL; N-PAC
NCBI Protein Information
putative oxidoreductase GLYR1
UniProt Protein Name
Putative oxidoreductase GLYR1
UniProt Gene Name
GLYR1
UniProt Synonym Gene Names
HIBDL; NP60

Uniprot Description

Putative oxidoreductase that is recruited on chromatin and promotes KDM1B demethylase activity (PubMed:23260659). Recognizes and binds trimethylated 'Lys-36' of histone H3 (H3K36me3) (PubMed:20850016). Regulates p38 MAP kinase activity by mediating stress activation of p38alpha/MAPK14 and specifically regulating MAPK14 signaling (PubMed:16352664). Indirectly promotes phosphorylation of MAPK14 and activation of ATF2 (PubMed:16352664). The phosphorylation of MAPK14 requires upstream activity of MAP2K4 and MAP2K6 (PubMed:16352664).

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Product Notes

The NP60 glyr1 (Catalog #AAA8292688) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NP60 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NP60 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1/500 - 1/2000. Researchers should empirically determine the suitability of the NP60 glyr1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NP60, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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