Rabbit anti-Mouse NME3 Polyclonal Antibody | anti-NME3 antibody

NME3 Rabbit pAb

Cat. Num. AAA4757830

• Gene Names: NME3; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
• Reactivity: Mouse
• Applications: ELISA, Western Blot
• Purity: Affinity purified
• Synonyms: NME3; Polyclonal Antibody; NME3 Rabbit pAb; NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2; anti-NME3 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Purity/Purification: Affinity purified
• Form/Format: -20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

• Applicable Applications for anti-NME3 antibody: ELISA (EIA), Western Blot (WB)
• Application Notes: WB: 1:1000-1:5000
• Immunogen: Fusion protein of human NME3
• Conjugation: Unconjugated
• Molecular Function: Nucleoside diphosphate kinase 3 is an enzyme that in humans is encoded by the NME3 gene. Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis.
• Modification: Unmodified
• Preparation and Storage: Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.

Western Blot (WB)

(Gel: 12%SDS-PAGE, Lysate: 40 ug, Lane: Mouse kidney tissue, Primary antibody: 821042(NME3 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)

Product Categories/Family for anti-NME3 antibody

Primary antibody

NCBI and Uniprot Product Information

• NCBI GI #: 12652978
• NCBI GeneID: 4832
• UniProt Accession #: Q13232; Q9BWH4
• Molecular Weight: 19,015 Da
• NCBI Official Full Name: Homo sapiens non-metastatic cells 3, protein expressed in, mRNA
• NCBI Official Synonym Full Names: NME/NM23 nucleoside diphosphate kinase 3
• NCBI Official Symbol: NME3
• NCBI Official Synonym Symbols: NDPKC; NDPK-C; NM23H3; DR-nm23; NM23-H3; c371H6.2
• NCBI Protein Information: nucleoside diphosphate kinase 3
• UniProt Protein Name: Nucleoside diphosphate kinase 3
• Protein Family: Nucleoside diphosphate kinase
• UniProt Gene Name: NME3
• UniProt Synonym Gene Names: NDK 3; NDP kinase 3; NDPKC
• UniProt Entry Name: NDK3_HUMAN

Uniprot Description

NME3: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Probably has a role in normal hematopoiesis by inhibition of granulocyte differentiation and induction of apoptosis. Belongs to the NDK family.

Protein type: Kinase, other; Kinase, nucleoside diphosphate; Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Apoptosis; Motility/polarity/chemotaxis; Nucleotide Metabolism - purine; Other group; NDK family

Chromosomal Location of Human Ortholog: 16q13.3

Cellular Component: mitochondrion; cytosol

Molecular Function: metal ion binding; nucleoside diphosphate kinase activity; ATP binding

Biological Process: GTP biosynthetic process; regulation of apoptosis; CTP biosynthetic process; apoptosis; pyrimidine nucleotide metabolic process; UTP biosynthetic process; nucleoside triphosphate biosynthetic process; nucleoside diphosphate phosphorylation; purine nucleotide metabolic process