Rabbit NIBP Polyclonal Antibody | anti-TRAPPC9 antibody
NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1)
Serum
Serum
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein that likely plays a role in NF-kappa-B signaling. Mutations in this gene have been associated with autosomal-recessive mental retardation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Feb 2010]
Uniprot Description
NIBP: Functions as an activator of NF-kappa-B through increased phosphorylation of the IKK complex. May function in neuronal cells differentiation. May play a role in vesicular transport from endoplasmic reticulum to Golgi. Defects in TRAPPC9 are the cause of mental retardation autosomal recessive type 13 (MRT13). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Brain magnetic resonance imaging of MRT13 patients indicates the presence of mild cerebral white matter hypoplasia. Microcephaly is present in some but not all affected individuals. Belongs to the NIBP family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Activator
Chromosomal Location of Human Ortholog: 8q24.3
Cellular Component: Golgi apparatus; endoplasmic reticulum
Biological Process: cell differentiation
Disease: Mental Retardation, Autosomal Recessive 13
Research Articles on TRAPPC9
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Product Notes
The TRAPPC9 trappc9 (Catalog #AAA645127) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NIBP (Trafficking Protein Particle Complex Subunit 9, NIK- and IKBKB-binding Protein, Tularik Gene 1 Protein, TRAPPC9, KIAA1882, T1) reacts with Bovine, Canine, Chicken, Human, Monkey, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's NIBP can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF). Suitable for use in Immunofluorescence, Western Blot, Immunocytochemistry and Immunoprecipitation. Researchers should empirically determine the suitability of the TRAPPC9 trappc9 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NIBP, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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