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Testing Data

Rabbit NGN2 Polyclonal Antibody | anti-NGN2 antibody

NGN2 Antibody (CT)

Gene Names
NEUROG2; NGN2; Atoh4; ngn-2; Math4A; bHLHa8
Reactivity
Human, Mouse, Rat
Applications
Western Blot, ELISA
Purity
Affinity chromatography purified via peptide column
Synonyms
NGN2; Polyclonal Antibody; NGN2 Antibody (CT); Neurogenin-2; Neurog2; NGN-2; atonal homolog 4; atoh4; math4a; basic helix-loop-helix protein 8; bHLHa8; anti-NGN2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG1
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
100 ug (1 mg/ml) in 1X PBS containing 1 mg/ml BSA, 50% glycerol and less than 0.02% sodium azide, pH 7.4.
Appearance: Colorless liquid
Concentration
1 mg/ml (varies by lot)
Sequence Length
272
Applicable Applications for anti-NGN2 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
Western Blot: 1 - 2 mug/ml, ELISA. However, the optimal conditions should be determined individually.
Immunogen
Rabbit polyclonal NGN2 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human NGN2.
Positive Control
Western Blot: Rat brain tissue lysate
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months

Testing Data

Testing Data
Related Product Information for anti-NGN2 antibody
Background: Neurogenin-2 (NGN2) is a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. NGN2 is thomught to work with Nurr1 to play a role in the differentiation and survival of midbrain dopaminergic neurons. It has also been smuggested for use in human embryonic neural progenitors as a graft for spinal cord injuries

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
28,621 Da
NCBI Official Full Name
neurogenin-2
NCBI Official Synonym Full Names
neurogenin 2
NCBI Official Symbol
NEUROG2
NCBI Official Synonym Symbols
NGN2; Atoh4; ngn-2; Math4A; bHLHa8
NCBI Protein Information
neurogenin-2
UniProt Protein Name
Neurogenin-2
UniProt Gene Name
NEUROG2
UniProt Synonym Gene Names
ATOH4; BHLHA8; NGN2; NGN-2; bHLHa8
UniProt Entry Name
NGN2_HUMAN

NCBI Description

This gene encodes a neural-specific basic helix-loop-helix (bHLH) transcription factor that can specify a neuronal fate on ectodermal cells and is expressed in neural progenitor cells within the developing central and peripheral nervous systems. The protein product of this gene also plays a role in the differentiation and survival of midbrain dopaminergic neurons. [provided by RefSeq, Apr 2012]

Uniprot Description

neurogenin 2: Transcriptional regulator. Involved in neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3').

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: nucleus

Molecular Function: protein dimerization activity; sequence-specific DNA binding

Biological Process: axon guidance; cell fate commitment; transcription, DNA-dependent; forebrain development; cell maturation; neuron migration; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription factor activity; positive regulation of neuron differentiation; central nervous system neuron development

Research Articles on NGN2

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Product Notes

The NGN2 neurog2 (Catalog #AAA841196) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NGN2 Antibody (CT) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NGN2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). Western Blot: 1 - 2 mug/ml, ELISA. However, the optimal conditions should be determined individually. Researchers should empirically determine the suitability of the NGN2 neurog2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NGN2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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