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Western Blot (WB) (Western blot analysis of extracts from HeLa cells, using NFE2L3 antibody.)

Rabbit anti-Human NFE2L3 Polyclonal Antibody | anti-NFE2L3 antibody

NFE2L3 Antibody

Gene Names
NFE2L3; NRF3
Reactivity
Human
Applications
Western Blot
Purity
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
NFE2L3; Polyclonal Antibody; NFE2L3 Antibody; Nuclear factor erythroid 2-related factor 3; NF-E2-related factor 3; NFE2-related factor 3; Nuclear factor; erythroid derived 2; anti-NFE2L3 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
The antibody detects endogenous levels of total NFE2L3 protein.
Purity/Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
694
Applicable Applications for anti-NFE2L3 antibody
Western Blot (WB)
Application Notes
Western blotting: 1:500~1:3000
Immunogen Type
Peptide
Immunogen Description
Synthesized peptide derived from internal of human NFE2L3.
Target Name
NFE2L3
Preparation and Storage
Store at -20 degree C

Western Blot (WB)

(Western blot analysis of extracts from HeLa cells, using NFE2L3 antibody.)

Western Blot (WB) (Western blot analysis of extracts from HeLa cells, using NFE2L3 antibody.)
Related Product Information for anti-NFE2L3 antibody
Activates erythroid-specific, globin gene expression.Blank V., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.Stoesz S.P., Submitted (MAR-1999) to the EMBL/GenBank/DDBJ databases.Hillier L.W., Nature 424:157-164(2003).
Product Categories/Family for anti-NFE2L3 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
76,154 Da
NCBI Official Full Name
nuclear factor erythroid 2-related factor 3
NCBI Official Synonym Full Names
nuclear factor, erythroid 2-like 3
NCBI Official Symbol
NFE2L3
NCBI Official Synonym Symbols
NRF3
NCBI Protein Information
nuclear factor erythroid 2-related factor 3
UniProt Protein Name
Nuclear factor erythroid 2-related factor 3
UniProt Gene Name
NFE2L3
UniProt Synonym Gene Names
NRF3; NF-E2-related factor 3; NFE2-related factor 3
UniProt Entry Name
NF2L3_HUMAN

NCBI Description

This gene encodes a member of the cap 'n' collar basic-region leucine zipper family of transcription factors. The encoded protein heterodimerizes with small musculoaponeurotic fibrosarcoma factors to bind antioxidant response elements in target genes. This protein is a membrane bound glycoprotein that is targeted to the endoplasmic reticulum and the nuclear envelope. Pseudogenes of this gene are found on chromosomes 16, 17, and 18. [provided by RefSeq, Mar 2009]

Uniprot Description

NFE2L3: Activates erythroid-specific, globin gene expression. Belongs to the bZIP family. CNC subfamily.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 7p15.2

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; transcription coactivator activity; transcription factor activity

Biological Process: negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter; transcription from RNA polymerase II promoter

Research Articles on NFE2L3

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Product Notes

The NFE2L3 nfe2l3 (Catalog #AAA9402369) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NFE2L3 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NFE2L3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western blotting: 1:500~1:3000. Researchers should empirically determine the suitability of the NFE2L3 nfe2l3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NFE2L3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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