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Goat Neurogenin 1 Polyclonal Antibody | anti-NEUROG1 antibody

Goat anti-Neurogenin 1 Antibody

Gene Names
NEUROG1; AKA; ngn1; Math4C; bHLHa6; NEUROD3
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
Neurogenin 1; Polyclonal Antibody; Goat anti-Neurogenin 1 Antibody; NEUROG1; neurogenin 1; AKA; Math4C; NEUROD3; ngn1; neurogenic differentiation 3; NEUROG1 antibody; neurogenin 1 antibody; AKA antibody; Math4C antibody; NEUROD3 antibody; ngn1 antibody; neurogenic differentiation 3 antibody; anti-NEUROG1 antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human, Mouse, Rat, Dog
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
KDLLHTTPCFIPYH
Sequence Length
237
Applicable Applications for anti-NEUROG1 antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 8000.
Western Blot: Preliminary experiments gave an approx 37kDa band in nuclear lysates of cell line HeLa after 2ug/ml antibody staining. The 37kDa band was successfully blocked by incubation with the immunizing peptide.
Immunogen
Peptide with sequence KDLLHTTPCFIPYH, from the C Terminus of the protein sequence according to NP_006152.2.
Epitope
C Terminus
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,718 Da
NCBI Official Full Name
neurogenin-1
NCBI Official Synonym Full Names
neurogenin 1
NCBI Official Symbol
NEUROG1
NCBI Official Synonym Symbols
AKA; ngn1; Math4C; bHLHa6; NEUROD3
NCBI Protein Information
neurogenin-1
UniProt Protein Name
Neurogenin-1
Protein Family
UniProt Gene Name
NEUROG1
UniProt Synonym Gene Names
BHLHA6; NEUROD3; NGN; NGN1; NGN-1; bHLHa6; NeuroD3
UniProt Entry Name
NGN1_HUMAN

Uniprot Description

neurogenin 1: Acts as a transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box (5'-CANNTG-3'). Associates with chromatin to enhancer regulatory elements in genes encoding key transcriptional regulators of neurogenesis.

Protein type: DNA-binding; Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 5q23-q31

Cellular Component: nucleus; perikaryon

Molecular Function: chromatin binding; DNA binding; protein binding; protein dimerization activity; transcription factor activity

Biological Process: cell fate commitment; inner ear morphogenesis; nervous system development; neuron differentiation; positive regulation of exit from mitosis; positive regulation of neuron differentiation; positive regulation of transcription factor activity; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent

Research Articles on NEUROG1

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Product Notes

The NEUROG1 neurog1 (Catalog #AAA420633) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Neurogenin 1 Antibody reacts with Expected from sequence similarity: Human, Mouse, Rat, Dog and may cross-react with other species as described in the data sheet. AAA Biotech's Neurogenin 1 can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 8000. Western Blot: Preliminary experiments gave an approx 37kDa band in nuclear lysates of cell line HeLa after 2ug/ml antibody staining. The 37kDa band was successfully blocked by incubation with the immunizing peptide. Researchers should empirically determine the suitability of the NEUROG1 neurog1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: KDLLHTTPCF IPYH. It is sometimes possible for the material contained within the vial of "Neurogenin 1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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