Goat NeuroD4 Polyclonal Antibody | anti-NEUROD4 antibody

NeuroD4 (Zinc Finger Protein Neuro-d4, BRG1-associated Factor 45B, BAF45B, D4, Zinc and Double PHD Fingers Family 1, DPF1, BAF45B, NEUD4)

Cat. Num. AAA6011068

• Gene Names: NEUROD4; ATH3; ATH-3; Atoh3; MATH-3; bHLHa4
• Reactivity: Bovine, Human, Mouse, Rat
• Applications: ELISA, Western Blot
• Purity: Affinity Purified; Purified by immunoaffinity chromatography.
• Synonyms: NeuroD4; Polyclonal Antibody; NeuroD4 (Zinc Finger Protein Neuro-d4; BRG1-associated Factor 45B; BAF45B; D4; Zinc and Double PHD Fingers Family 1; DPF1; NEUD4); Anti -NeuroD4 (Zinc Finger Protein Neuro-d4; anti-NEUROD4 antibody

• Host: Goat
• Reactivity: Bovine, Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Recognizes human Neuro-d4. Species sequence homology: Bovine, mouse and rat.
• Purity/Purification: Affinity Purified; Purified by immunoaffinity chromatography.
• Form/Format: Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

• Applicable Applications for anti-NEUROD4 antibody: ELISA (EL/EIA), Western Blot (WB)
• Application Notes: Suitable for use in ELISA and Western Blot.; Dilution: ELISA: 1:2000; Western Blot: 1-3ug/ml
• Immunogen: Synthetic peptide corresponding to C-HLKEKASAYITLT, from human Neuro-d4, at C-terminal (NP_001128627.1, NP_004638.2, NP_001128628.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Chemiluminescence

(1ug/ml staining of Human Brain (Cerebellum) lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)

Product Categories/Family for anti-NEUROD4 antibody

Antibodies; Abs to Transcription Factors; Zinc (Ring) Finger

NCBI and Uniprot Product Information

• NCBI GI #: 153792190
• NCBI GeneID: 58158
• NCBI Accession #: NP_067014.2
• NCBI GenBank Nucleotide #: NM_021191.2
• UniProt Accession #: Q9HD90; B2RAC9
• Molecular Weight: 37,041 Da
• NCBI Official Full Name: neurogenic differentiation factor 4
• NCBI Official Synonym Full Names: neuronal differentiation 4
• NCBI Official Symbol: NEUROD4
• NCBI Official Synonym Symbols: ATH3; ATH-3; Atoh3; MATH-3; bHLHa4
• NCBI Protein Information: neurogenic differentiation factor 4; protein atonal homolog 3; neurogenic differentiation 4; class A basic helix-loop-helix protein 4
• UniProt Protein Name: Neurogenic differentiation factor 4
• Protein Family: Neurogenic differentiation factor
• UniProt Gene Name: NEUROD4
• UniProt Synonym Gene Names: ATH3; ATOH3; BHLHA4; NeuroD4; bHLHa4; ATH-3; Atoh3
• UniProt Entry Name: NDF4_HUMAN

Uniprot Description

NEUROD4: Probably acts as a transcriptional activator. Mediates neuronal differentiation. Required for the regulation of amacrine cell fate specification in the retina.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 12q13.2

Cellular Component: nucleus

Molecular Function: protein dimerization activity; DNA binding

Biological Process: Notch signaling pathway; cell fate commitment; glial cell differentiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; neuroblast proliferation; neuron migration; neuron development; positive regulation of cell differentiation