Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: HEPG2 cell lysate, Primary antibody: 863506(NTNG2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Rabbit anti-Human Netrin G2 Polyclonal Antibody | anti-NTNG2 antibody
Netrin G2 Rabbit pAb
Gene Names
NTNG2; Lmnt2; NTNG1; LHLL9381; bA479K20.1
Reactivity
Human
Applications
ELISA, Western Blot
Purity
Affinity purified
Synonyms
Netrin G2; Polyclonal Antibody; Netrin G2 Rabbit pAb; Lmnt2; NTNG1; LHLL9381; bA479K20.1; anti-NTNG2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
-20 degree C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Applicable Applications for anti-NTNG2 antibody
ELISA (EIA), Western Blot (WB)
Application Notes
WB: 1:200-1:1000
Immunogen
Synthetic peptide of human NTNG2
Conjugation
Unconjugated
Molecular Function
Netrin G1 and Netrin G2, also referred to as laminet-1 and laminet-2, are membrane bound axon guidance molecules involved in synaptic formation and maintenance. They comprise a subgroup within the UNC-6/netrin family. Both genes have been associated with schizophrenia involving single nucleotide polymorphisms. They are both expressed in the brain but G1 is most predominantly expressed in the thalamus and G2 is most predominantly expressed in the cortex and hippocampus. These two proteins differ from classical netrins by their failure to bind netrin receptors, the presence of a glycosyl phosphatidylinositol membrane anchor, and the generation of multiple isoforms. Netrin G2 contains one laminin N-terminal domain and three laminin EGF-like domains. It selectively interacts with LRRC4 and this association may mediate cell adhesion. In addition, Netrin G2 is significantly downregulated in bladder transitional cell carcinoma (TCC) and may be a putative tumor suppressor gene.
Modification
Unmodified
Cell Position
Cell membrane, Membrane
Preparation and Storage
Store at 4 degree C for short term. Store at -20 degree C for long term. Avoid freeze/thaw cycle.
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: HEPG2 cell lysate, Primary antibody: 863506(NTNG2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Western Blot (WB)
(Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: HEPG2 cell lysate, Primary antibody: 863506(NTNG2 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute)
Product Categories/Family for anti-NTNG2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
60kDa
NCBI Official Full Name
netrin-G2
NCBI Official Synonym Full Names
netrin G2
NCBI Official Symbol
NTNG2
NCBI Official Synonym Symbols
Lmnt2; NTNG1; LHLL9381; bA479K20.1
NCBI Protein Information
netrin-G2
UniProt Protein Name
Netrin-G2
Protein Family
UniProt Gene Name
NTNG2
UniProt Synonym Gene Names
KIAA1857; LMNT2
UniProt Entry Name
NTNG2_HUMAN
Uniprot Description
NTNG2: Promotes neurite outgrowth of both axons and dendrites. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, GPI anchor; Cell development/differentiation
Chromosomal Location of Human Ortholog: 9q34
Cellular Component: anchored to plasma membrane; axon
Molecular Function: protein binding
Biological Process: axonogenesis
Research Articles on NTNG2
Similar Products
Product Notes
The NTNG2 ntng2 (Catalog #AAA4758692) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Netrin G2 Rabbit pAb reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Netrin G2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB). WB: 1:200-1:1000. Researchers should empirically determine the suitability of the NTNG2 ntng2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Netrin G2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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