Goat Netrin-4 Polyclonal Antibody | anti-NTN4 antibody
Netrin-4 (PRO3091, NTN4, FLJ23180, Beta-netrin)
Gene Names
NTN4; PRO3091
Purity
Affinity PurifiedPurified by immunoaffinity chromatography.
Synonyms
Netrin-4; Polyclonal Antibody; Netrin-4 (PRO3091; NTN4; FLJ23180; Beta-netrin); Anti -Netrin-4 (PRO3091; anti-NTN4 antibody
Host
Goat
Clonality
Polyclonal
Specificity
Recognizes NTN4. Species sequence homology: Human, mouse, caninie and bovine.
Purity/Purification
Affinity Purified
Purified by immunoaffinity chromatography.
Purified by immunoaffinity chromatography.
Form/Format
Supplied as a liquid in tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
Application Notes
Suitable for use in ELISA.
Dilution: ELISA: 1:32000
Dilution: ELISA: 1:32000
Immunogen
Synthetic peptide corresponding to SENTDLTCRQPK, aa65-76 of NTN4.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Related Product Information for anti-NTN4 antibody
Netrin-4 is a 628 amino acid laminin-related secreted protein that promotes neurite elongation at low concentrations but inhibits neurite extension at high concentrations. Recent evidence suggest that Netrin family members act as regulators of both neuronal and vascular growth and are implicated in controling epithelial cell branching morphogenesis in the pancreas, breast and lung. Netrin-4 inhibits proliferation of a variety of human tumor cells. Netrin-4 also induces proliferation, migration, adhesion, tube formation and survival of human lymphatic endothelial cells and seems to function as a lymphangiogenic factor contributing to tumor dissemination.
Product Categories/Family for anti-NTN4 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
70,071 Da
NCBI Official Full Name
netrin-4
NCBI Official Synonym Full Names
netrin 4
NCBI Official Symbol
NTN4
NCBI Official Synonym Symbols
PRO3091
NCBI Protein Information
netrin-4; beta-netrin; hepar-derived netrin-like protein
UniProt Protein Name
Netrin-4
Protein Family
UniProt Gene Name
NTN4
UniProt Entry Name
NET4_HUMAN
NCBI Description
NTN4 belongs to a family of proteins related to laminins (see LAMA1, MIM 150320) Koch et al. (2000) [PubMed 11038171].[supplied by OMIM, Mar 2008]
Uniprot Description
NTN4: May play an important role in neural, kidney and vascular development. Promotes neurite elongation from olfactory bulb explants. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 12q22
Cellular Component: plasma membrane; basement membrane
Molecular Function: laminin-1 binding
Biological Process: axon guidance; extracellular matrix organization and biogenesis; neuron remodeling
Research Articles on NTN4
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Product Notes
The NTN4 ntn4 (Catalog #AAA6005633) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. Suitable for use in ELISA. Dilution: ELISA: 1:32000. Researchers should empirically determine the suitability of the NTN4 ntn4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Netrin-4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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