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Sheep Nerve Growth Factor 2.5S Polyclonal Antibody | anti-Beta-NGF antibody

Nerve Growth Factor 2.5S (Beta-Nerve Growth Factor, Beta-NGF, Ngf, Ngfb) (FITC)

Gene Names
Ngf; Ngfb
Reactivity
Mouse, Human, Rat
Applications
ELISA, Functional Assay, Western Blot
Purity
Purified
Synonyms
Nerve Growth Factor 2.5S; Polyclonal Antibody; Nerve Growth Factor 2.5S (Beta-Nerve Growth Factor; Beta-NGF; Ngf; Ngfb) (FITC); anti-Beta-NGF antibody
Ordering
For Research Use Only!
Host
Sheep
Reactivity
Mouse, Human, Rat
Clonality
Polyclonal
Isotype
IgG
Specificity
Recognizes the beta subunit of mouse NGF in both the 2.5S and 7S forms. It does not react with mice serum proteins, renin or epidermal growth factor. Species Crossreactivity: rat and human
Purity/Purification
Purified
Form/Format
Supplied as a liquid in PBS, pH 7.2. Labeled with Fluorescein Isothiocyanate (FITC).
Applicable Applications for anti-Beta-NGF antibody
ELISA (EIA), Functional Assay, Western Blot (WB)
Application Notes
Applications are based on unconjugated antibody.
Immunogen
Affinity purified mouse 2.5S NGF
Conjugate
FITC
Note
Preservative Free
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Related Product Information for anti-Beta-NGF antibody
NGF is a multimeric protein that promotes nerve cell growth and may protect some types of nerve cells from damage, including nerve cells in the cholinergic system.
Product Categories/Family for anti-Beta-NGF antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
27,077 Da
NCBI Official Full Name
beta-nerve growth factor isoform B
NCBI Official Synonym Full Names
nerve growth factor
NCBI Official Symbol
Ngf
NCBI Official Synonym Symbols
Ngfb
NCBI Protein Information
beta-nerve growth factor; beta-NGF; nerve growth factor, beta
UniProt Protein Name
Beta-nerve growth factor
UniProt Gene Name
Ngf
UniProt Synonym Gene Names
Ngfb; Beta-NGF
UniProt Entry Name
NGF_MOUSE

Uniprot Description

NGF: Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival. Homodimer. Belongs to the NGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cytoplasmic membrane-bound vesicle; extracellular region

Molecular Function: metalloendopeptidase inhibitor activity; nerve growth factor receptor binding; growth factor activity; receptor signaling protein activity; receptor binding

Biological Process: positive regulation of neuron maturation; adult locomotory behavior; regulation of neuron differentiation; positive regulation of axon extension; regulation of neurotransmitter secretion; sensory perception of pain; positive regulation of cell growth; positive regulation of protein amino acid autophosphorylation; positive regulation of nerve growth factor receptor signaling pathway; regulation of release of sequestered calcium ion into cytosol; memory; peripheral nervous system development; neuron apoptosis; induction of apoptosis via death domain receptors; positive regulation of cell proliferation; positive regulation of transcription factor activity; negative regulation of neuron apoptosis; positive regulation of neuron differentiation; positive regulation of collateral sprouting; transmembrane receptor protein tyrosine kinase signaling pathway; neurite development; neurite morphogenesis

Research Articles on Beta-NGF

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Product Notes

The Beta-NGF ngf (Catalog #AAA6489739) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The Nerve Growth Factor 2.5S (Beta-Nerve Growth Factor, Beta-NGF, Ngf, Ngfb) (FITC) reacts with Mouse, Human, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Nerve Growth Factor 2.5S can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Functional Assay, Western Blot (WB). Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the Beta-NGF ngf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Nerve Growth Factor 2.5S, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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