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Western Blot (WB) (Western blot analysis of NEP2 expression in OVCAR3 (A) whole cell lysates.)

Rabbit anti-Human NEP2 Polyclonal Antibody | anti-NEP2 antibody

Anti-NEP2 Antibody

Gene Names
MMEL1; NL1; NL2; SEP; NEP2; MMEL2; NEPII
Reactivity
Human
Applications
Western Blot
Purity
Purified by Immunogen Affinity Chromatography
Synonyms
NEP2; Polyclonal Antibody; Anti-NEP2 Antibody; MELL1; MMEL2; Membrane metallo-endopeptidase-like 1; Membrane metallo-endopeptidase-like 2; NEP2(m); Neprilysin II; NEPII; Neprilysin-2; NL2; anti-NEP2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
Recognizes endogenous levels of NEP2 protein.
Purity/Purification
Purified by Immunogen Affinity Chromatography
Form/Format
Liquid in 0.42% Potassium Phosphate, 0.87% Sodium Chloride, pH 7.3, 30% Glycerol, and 0.01% Sodium Azide.
Applicable Applications for anti-NEP2 antibody
Western Blot (WB)
Application Notes
WB: 1:500-1:2000
Immunogen
KLH-conjugated synthetic peptide of human NEP2. The exact sequence is proprietary.
Preparation and Storage
Upon delivery aliquot and store at -20 degree C for one year. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot analysis of NEP2 expression in OVCAR3 (A) whole cell lysates.)

Western Blot (WB) (Western blot analysis of NEP2 expression in OVCAR3 (A) whole cell lysates.)
Related Product Information for anti-NEP2 antibody
Rabbit polyclonal antibody to NEP2

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
89.4
NCBI Official Full Name
membrane metallo-endopeptidase-like 1
NCBI Official Synonym Full Names
membrane metalloendopeptidase like 1
NCBI Official Symbol
MMEL1
NCBI Official Synonym Symbols
NL1; NL2; SEP; NEP2; MMEL2; NEPII
NCBI Protein Information
membrane metallo-endopeptidase-like 1
UniProt Protein Name
Membrane metallo-endopeptidase-like 1
Protein Family
UniProt Gene Name
MMEL1
UniProt Synonym Gene Names
MELL1; MMEL2; NEP2; NEPII; NEP2; NL2; NEP2(s)

NCBI Description

The protein encoded by this gene is a member of the neutral endopeptidase (NEP) or membrane metallo-endopeptidase (MME) family. Family members play important roles in pain perception, arterial pressure regulation, phosphate metabolism and homeostasis. This protein is a type II transmembrane protein and is thought to be expressed as a secreted protein. This gene is expressed mainly in testis with weak expression in the brain, kidney, and heart. [provided by RefSeq, Jul 2008]

Uniprot Description

MELL1: Metalloprotease involved in sperm function, possibly by modulating the processes of fertilization and early embryonic development. Degrades a broad variety of small peptides with a preference for peptides shorter than 3 kDa containing neutral bulky aliphatic or aromatic amino acid residues. Shares the same substrate specificity with MME and cleaves peptides at the same amide bond. Belongs to the peptidase M13 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.24.11; Membrane protein, integral; Protease

Chromosomal Location of Human Ortholog: 1p36.32

Research Articles on NEP2

Similar Products

Product Notes

The NEP2 mmel1 (Catalog #AAA8307290) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-NEP2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NEP2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). WB: 1:500-1:2000. Researchers should empirically determine the suitability of the NEP2 mmel1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NEP2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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