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Western Blot (WB) (NELF Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the NELF antibody detected the NELF protein (arrow).)

Rabbit anti-Human NELF Polyclonal Antibody | anti-NELF antibody

NELF, CT (NELF, Nasal embryonic luteinizing hormone-releasing hormone factor) (FITC)

Gene Names
NSMF; HH9; NELF
Reactivity
Human
Applications
Western Blot
Purity
Purified by Protein A Affinity Chromatography.
Synonyms
NELF; Polyclonal Antibody; CT (NELF; Nasal embryonic luteinizing hormone-releasing hormone factor) (FITC); Nasal embryonic luteinizing hormone-releasing hormone factor; anti-NELF antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Protein A Affinity Chromatography.
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Fluorescein Isothiocyanate (FITC).
Sequence Length
507
Applicable Applications for anti-NELF antibody
Western Blot (WB), FLISA
Application Notes
WB: 1:100-500
FLISA: 1:1,000
Applications are based on unconjugated antibody.
Immunogen
NELF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 500-530 amino acids from the C-terminal region of human NELF.
Conjugate
FITC
Note
Preservative Free
Special Handling
Light sensitive
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(NELF Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the NELF antibody detected the NELF protein (arrow).)

Western Blot (WB) (NELF Antibody (C-term) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the NELF antibody detected the NELF protein (arrow).)
Related Product Information for anti-NELF antibody
The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene.
Product Categories/Family for anti-NELF antibody
References
Xu, N., et al. Mol. Cell. Endocrinol. 319 (1-2), 47-55 (2010): Trarbach, E.B., et al. Clin. Endocrinol. (Oxf) 72(3):371-376(2010). Yung, T.M., et al. Exp. Cell Res. 315(10):1693-1705(2009). Pedersen-White, J.R., et al. Mol. Hum. Reprod. 14(6):367-370(2008). Lim, J., et al. Cell 125(4):801-814(2006).

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
NMDA receptor synaptonuclear signaling and neuronal migration factor isoform c
NCBI Official Synonym Full Names
NMDA receptor synaptonuclear signaling and neuronal migration factor
NCBI Official Symbol
NSMF
NCBI Official Synonym Symbols
HH9; NELF
NCBI Protein Information
NMDA receptor synaptonuclear signaling and neuronal migration factor
UniProt Protein Name
NMDA receptor synaptonuclear signaling and neuronal migration factor
UniProt Gene Name
NSMF
UniProt Synonym Gene Names
NELF; Nasal embryonic LHRH factor
UniProt Entry Name
NSMF_HUMAN

NCBI Description

The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]

Uniprot Description

NSMF: Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons. Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH). IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cortical cytoskeleton; nuclear membrane; neuron projection; nuclear matrix; postsynaptic density; dendrite; nuclear envelope; perikaryon; nucleoplasm; postsynaptic membrane; membrane; cytoplasm; synapse; nucleus; cell junction

Molecular Function: calcium-dependent protein binding

Biological Process: regulation of dendrite morphogenesis; regulation of neuron apoptosis; positive regulation of protein amino acid dephosphorylation; regulation of neuronal synaptic plasticity

Disease: Hypogonadotropic Hypogonadism 9 With Or Without Anosmia

Research Articles on NELF

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Product Notes

The NELF nsmf (Catalog #AAA6324653) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NELF, CT (NELF, Nasal embryonic luteinizing hormone-releasing hormone factor) (FITC) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NELF can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), FLISA. WB: 1:100-500 FLISA: 1:1,000 Applications are based on unconjugated antibody. Researchers should empirically determine the suitability of the NELF nsmf for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NELF, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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