Immunohistochemistry (IHC)
(NDUFC2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NDUFC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Rabbit anti-Human NDUFC2 Polyclonal Antibody | anti-NDUFC2 antibody
NDUFC2 Antibody (C-term)
Gene Names
NDUFC2; HLC-1; B14.5b; NADHDH2; CI-B14.5b
Reactivity
Human
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
NDUFC2; Polyclonal Antibody; NDUFC2 Antibody (C-term); NADH dehydrogenase [ubiquinone] 1 subunit C2; Complex I-B145b; CI-B145b; Human lung cancer oncogene 1 protein; HLC-1; NADH-ubiquinone oxidoreductase subunit B145b; anti-NDUFC2 antibody
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This NDUFC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 90-119 amino acids from the C-terminal region of human NDUFC2.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
90-119
Sequence Length
88
Applicable Applications for anti-NDUFC2 antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes
IHC~~1:50~100
WB~~1:1000
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
HUMAN
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.
Immunohistochemistry (IHC)
(NDUFC2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NDUFC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(NDUFC2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NDUFC2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Western Blot (WB)
(NDUFC2 Antibody (C-term) western blot analysis in MDA-MB453,Hela,293 cell line lysates (35ug/lane).This demonstrates the NDUFC2 antibody detected the NDUFC2 protein (arrow).)
Western Blot (WB)
(NDUFC2 Antibody (C-term) western blot analysis in MDA-MB453,Hela,293 cell line lysates (35ug/lane).This demonstrates the NDUFC2 antibody detected the NDUFC2 protein (arrow).)
Related Product Information for anti-NDUFC2 antibody
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
Product Categories/Family for anti-NDUFC2 antibody
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Wheeler, H.E., et al. PLoS Genet. 5 (10), E1000685 (2009) :
Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008)
Starr, J.M., et al. Mech. Ageing Dev. 129(12):745-751(2008)
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
14188
NCBI Official Full Name
NADH dehydrogenase
NCBI Official Synonym Full Names
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2, 14.5kDa
NCBI Official Symbol
NDUFC2
NCBI Official Synonym Symbols
HLC-1; B14.5b; NADHDH2; CI-B14.5b
NCBI Protein Information
NADH dehydrogenase [ubiquinone] 1 subunit C2
UniProt Protein Name
NADH dehydrogenase [ubiquinone] 1 subunit C2
Protein Family
UniProt Gene Name
NDUFC2
UniProt Synonym Gene Names
CI-B14.5b; HLC-1
UniProt Entry Name
NDUC2_HUMAN
Uniprot Description
NDUFC2: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFC2 subunit family.
Protein type: Mitochondrial; Membrane protein, integral; Energy Metabolism - oxidative phosphorylation
Chromosomal Location of Human Ortholog: 11q14.1
Cellular Component: mitochondrial inner membrane; cytoplasm; integral to membrane; mitochondrial respiratory chain complex I
Molecular Function: NADH dehydrogenase (ubiquinone) activity
Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone
Research Articles on NDUFC2
Similar Products
Product Notes
The NDUFC2 ndufc2 (Catalog #AAA9205437) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 90-119. The NDUFC2 Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NDUFC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). IHC~~1:50~100 WB~~1:1000. Researchers should empirically determine the suitability of the NDUFC2 ndufc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDUFC2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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