Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Raji cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds)
Rabbit anti-Human NDUFAF4 Polyclonal Antibody | anti-NDUFAF4 antibody
NDUFAF4 Antibody
Immunohistochemistry: 1:50-1:200
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Raji cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds)
Testing Data
(Gel: 10%SDS-PAGE Lysate: 40ug Raji cell Primary antibody: 1/300 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 seconds)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/45.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue using at dilution 1/45.)
NCBI and Uniprot Product Information
NCBI Description
NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. [provided by RefSeq, Oct 2009]
Uniprot Description
NDUFAF4: Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion. Defects in NDUFAF4 are a cause of mitochondrial complex I deficiency (MT-C1D). A disorder of the mitochondrial respiratory chain that causes a wide range of clinical disorders, from lethal neonatal disease to adult-onset neurodegenerative disorders. Phenotypes include macrocephaly with progressive leukodystrophy, non-specific encephalopathy, cardiomyopathy, myopathy, liver disease, Leigh syndrome, Leber hereditary optic neuropathy, and some forms of Parkinson disease. Belongs to the NDUFAF4 family.
Protein type: Mitochondrial; Apoptosis
Chromosomal Location of Human Ortholog: 6q16.1
Cellular Component: mitochondrion; mitochondrial membrane
Molecular Function: calmodulin binding; protein binding
Biological Process: mitochondrial respiratory chain complex I assembly
Disease: Mitochondrial Complex I Deficiency
Research Articles on NDUFAF4
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Product Notes
The NDUFAF4 ndufaf4 (Catalog #AAA9405653) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDUFAF4 Antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's NDUFAF4 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting: 1:500-1:2000 Immunohistochemistry: 1:50-1:200. Researchers should empirically determine the suitability of the NDUFAF4 ndufaf4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDUFAF4, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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