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Western Blot (WB) (Western blot analysis NDRG2 (Phospho-Thr348) using EGF treated 293 whole cell lysates)

Rabbit NDRG2 Polyclonal Antibody | anti-NDRG2 antibody

NDRG2 (Phospho-Thr348) Antibody

Gene Names
NDRG2; SYLD
Reactivity
Human, Mouse, Rat
Applications
Western Blot
Synonyms
NDRG2; Polyclonal Antibody; NDRG2 (Phospho-Thr348) Antibody; KIAA1248; N-myc downstream regulator 2; NDRG family member 2; SYLD; NDR1-related protein NDR2; Protein Syld709613; Syld709613 protein; Cytoplasmic protein Ndr1; Protein NDRG2; anti-NDRG2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Specificity
NDRG2 (Phospho-Thr348) Antibody detects endogenous levels of NDRG2 only when phosphorylated at Thr348
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration
1.0 mg/ml (varies by lot)
Sequence Length
367
Applicable Applications for anti-NDRG2 antibody
Western Blot (WB)
Application Notes
Western Blot: 1:1000
Immunogen
A synthesized peptide derived from human NDRG2 (Phospho-Thr348)
Immunogen Type
Peptide
Target Species
Human
Calculated MW
41 kD
Purification
Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Modification
Phospho-Thr348
Preparation and Storage
Store at -20°C

Western Blot (WB)

(Western blot analysis NDRG2 (Phospho-Thr348) using EGF treated 293 whole cell lysates)

Western Blot (WB) (Western blot analysis NDRG2 (Phospho-Thr348) using EGF treated 293 whole cell lysates)
Product Categories/Family for anti-NDRG2 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
NCBI Official Full Name
protein NDRG2 isoform c
NCBI Official Synonym Full Names
NDRG family member 2
NCBI Official Symbol
NDRG2
NCBI Official Synonym Symbols
SYLD
NCBI Protein Information
protein NDRG2
UniProt Protein Name
Protein NDRG2
Protein Family
UniProt Gene Name
NDRG2
UniProt Synonym Gene Names
KIAA1248; SYLD
UniProt Entry Name
NDRG2_HUMAN

NCBI Description

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Uniprot Description

NDRG2: a pro-apoptotic protein that may be involved in dendritic cell and neuron differentiation. May have anti-tumor activity. Generally not expressed in tumor cell lines. Unlike Ndr1, Ndr2 and Ndr3 appear not to be controlled by N-myc or c-myc. The loss of NDRG2 expression has been shown to be a prognostic indicator in gastric carcinomas. Five isoforms of the human protein are produced by alternative splicing. Isoforms 1 and 2 are present in brain neurons and up-regulated in Alzheimer disease

Protein type: Apoptosis; Tumor suppressor

Chromosomal Location of Human Ortholog: 14q11.2

Cellular Component: centrosome; cytoplasm; Golgi apparatus; microtubule organizing center; nucleoplasm

Molecular Function: protein binding

Biological Process: signal transduction; substantia nigra development

Research Articles on NDRG2

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Product Notes

The NDRG2 ndrg2 (Catalog #AAA9416707) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NDRG2 (Phospho-Thr348) Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NDRG2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Western Blot: 1:1000. Researchers should empirically determine the suitability of the NDRG2 ndrg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NDRG2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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