Western Blot (WB)
(Western blot detection of NCAPH2 in Hela,Jurkat cell lysates using NCAPH2 Rabbit pAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.)
Rabbit NCAPH2 Polyclonal Antibody | anti-NCAPH2 antibody
NCAPH2 Rabbit pAb
Gene Names
NCAPH2; CAPH2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Flow Cytometry, Functional Assay, Immunoprecipitation
Purity
Affinity purified
Synonyms
NCAPH2; Polyclonal Antibody; NCAPH2 Rabbit pAb; Condensin-2 complex subunit H2; non-SMC condensin II complex subunit H2; anti-NCAPH2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
Rabbit IgG
Purity/Purification
Affinity purified
Form/Format
Supplied in 50nM Tris-Glycine(pH7.4), 0.15M Nacl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA.
Applicable Applications for anti-NCAPH2 antibody
Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP)
Application Notes
WB: 1:1000
IHC: 1:20
ICC/IF: 1:20
FC/FACS: 1:20
IP: 1:20
IHC: 1:20
ICC/IF: 1:20
FC/FACS: 1:20
IP: 1:20
Immunogen
A synthetic peptide of human NCAPH2
Conjugation
Unconjugated
Modification
Unmodified
Preparation and Storage
Store at -20 degree C. Stable for 12 months from date of receipt.
Western Blot (WB)
(Western blot detection of NCAPH2 in Hela,Jurkat cell lysates using NCAPH2 Rabbit pAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.)
Western Blot (WB)
(Western blot detection of NCAPH2 in Hela,Jurkat cell lysates using NCAPH2 Rabbit pAb(1:1000 diluted).Predicted band size:68kDa.Observed band size:68kDa.)
Related Product Information for anti-NCAPH2 antibody
Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture (PubMed:14532007). May promote the resolution of double-strand DNA catenanes (intertwines) between sister chromatids. Condensin-mediated compaction likely increases tension in catenated sister chromatids, providing directionality for type II topoisomerase-mediated strand exchanges toward chromatid decatenation. Required for decatenation of chromatin bridges at anaphase. Early in neurogenesis, may play an essential role to ensure accurate mitotic chromosome condensation in neuron stem cells, ultimately affecting neuron pool and cortex size. Seems to have lineage-specific role in T-cell development (PubMed:14532007).
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]
Product Categories/Family for anti-NCAPH2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
68,227 Da
NCBI Official Full Name
condensin-2 complex subunit H2 isoform 3
NCBI Official Synonym Full Names
non-SMC condensin II complex, subunit H2
NCBI Official Symbol
NCAPH2
NCBI Official Synonym Symbols
CAPH2
NCBI Protein Information
condensin-2 complex subunit H2; kleisin beta; chromosome-associated protein H2; CAP-H2 subunit of the condensin II complex
UniProt Protein Name
Condensin-2 complex subunit H2
UniProt Gene Name
NCAPH2
UniProt Synonym Gene Names
CAPH2; hCAP-H2
UniProt Entry Name
CNDH2_HUMAN
NCBI Description
This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010]
Uniprot Description
NCAPH2: Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development. Belongs to the CND2 H2 (condensin-2 subunit 2) family. 4 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Endoplasmic reticulum; Cell cycle regulation
Chromosomal Location of Human Ortholog: 22q13.33
Cellular Component: nucleoplasm; membrane; chromosome
Molecular Function: protein binding
Biological Process: chromosome condensation; mitotic cell cycle
Research Articles on NCAPH2
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Product Notes
The NCAPH2 ncaph2 (Catalog #AAA4756819) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NCAPH2 Rabbit pAb reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's NCAPH2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry-Paraffin (IHC-P), Immunohistochemistry-Frozen (IHC-F), Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FC/FACS), Immunoprecipitation (IP). WB: 1:1000 IHC: 1:20 ICC/IF: 1:20 FC/FACS: 1:20 IP: 1:20. Researchers should empirically determine the suitability of the NCAPH2 ncaph2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NCAPH2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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