Rabbit anti-Mouse NCAM Polyclonal Antibody | anti-NCAM1 antibody

Anti-NCAM Antibody, Rabbit Polyclonal

Cat. Num. AAA8104176

• Gene Names: Ncam1; CD56; Ncam; E-NCAM; NCAM-1
• Reactivity: Mouse
• Applications: Immunohistochemistry
• Purity: Protein A & Antigen Affinity
• Synonyms: NCAM; Polyclonal Antibody; Anti-NCAM Antibody; Rabbit Polyclonal; NCAM1/CD56 Antibody; Rabbit PAb; Antigen Affinity Purified; neural cell adhesion molecule 1; Anti-CD56 Antibody; Anti-E-NCAM Antibody; Anti-Ncam Antibody; Anti-NCAM-1 Antibody; anti-NCAM1 antibody

• Host: Rabbit
• Reactivity: Mouse
• Clonality: Polyclonal
• Isotype: Rabbit IgG
• Specificity: Mouse NCAM1/CD56
• Purity/Purification: Protein A & Antigen Affinity
• Form/Format: Liquid; 0.2um filtered solution in PBS

• Applicable Applications for anti-NCAM1 antibody: Immunohistochemistry-Paraffin (IHC-P)
• Application Notes: IHC-P: 1:200-1:1000
• Immunogen: A synthetic peptide corresponding to the C-terminus of the Mouse NCAM1/CD56
• Conjugation: Unconjugated
• Preparation: Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Mouse NCAM1/CD56, and purified by antigen affinity chromatography.
• Preparation and Storage: This antibody can be stored at 2-8 degree C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20 degree C to -80 degree C. Preservative-Free. Avoid repeated freeze-thaw cycles.

Immunohistochemistry (IHC)

(Immunochemical staining of mouse CD56 in mouse brain with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)

Immunohistochemistry (IHC)

(Immunochemical staining of mouse CD56 in mouse colon with rabbit polyclonal antibody at 1:300 dilution, formalin-fixed paraffin embedded sections.)

Related Product Information for anti-NCAM1 antibody

NCAM1 (Neural Cell Adhesion Molecule 1, also known as CD56) is a Protein Coding gene. 3 alternatively spliced human isoforms have been reported. NCAM1 is a neural adhesion protein (NCAM) that belongs to the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. NCAM1 is involved in neuron-neuron adhesion, neurite fasciculation, the outgrowth of neurites, etc. It has also been shown to be involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Diseases associated with NCAM1 include Rabies and Bile Duct Cancer. Among its related pathways are Neuroscience and RET signaling.

References

Reyes AA. et al., 1991, Mol Cell Biol. 11 (3): 1654-61. Suzuki M. et al., 2003, J Biol Chem. 278 (49): 49459-68. Becker C G. et al., 1996, J Neurosci Res. 45 (2): 143-52.

NCBI and Uniprot Product Information

• NCBI GI #: 205830666
• NCBI GeneID: 17967
• UniProt Accession #: P13595; P13594; Q61949; Q61950; Q6LBU8; Q8BQ96; Q8C4B2; Q921P2; Q9R2A7
• Molecular Weight: 67,353 Da
• NCBI Official Full Name: Neural cell adhesion molecule 1
• NCBI Official Synonym Full Names: neural cell adhesion molecule 1
• NCBI Official Symbol: Ncam1
• NCBI Official Synonym Symbols: CD56; Ncam; E-NCAM; NCAM-1
• NCBI Protein Information: neural cell adhesion molecule 1; N-CAM-1
• UniProt Protein Name: Neural cell adhesion molecule 1
• Protein Family: Neural cell adhesion molecule
• UniProt Gene Name: Ncam1
• UniProt Synonym Gene Names: Ncam; N-CAM-1; NCAM-1
• UniProt Entry Name: NCAM1_MOUSE

Uniprot Description

NCAM1: This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral; Membrane protein, GPI anchor; Motility/polarity/chemotaxis

Cellular Component: cell surface; growth cone; membrane; cell soma; axon; integral to membrane; plasma membrane; intercellular junction; myelin sheath; external side of plasma membrane

Molecular Function: heparin binding; identical protein binding; protein binding; LRR domain binding; phosphatase binding

Biological Process: regulation of exocyst assembly; positive regulation of calcium-mediated signaling; thalamus development; response to cocaine; cell surface receptor linked signal transduction; learning and/or memory; homotypic cell-cell adhesion; response to lead ion; response to fluoxetine; neuron development; regulation of sensory perception of pain; cell adhesion; multicellular organismal response to stress; neurite development; aging; positive regulation of cardiac muscle cell proliferation