Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Rabbit anti-Rat Natriuretic Peptide Receptor 3 Polyclonal Antibody | anti-NPR3 antibody
Polyclonal Antibody to Natriuretic Peptide Receptor 3 (NPR3)
MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- AQKIEV LVLLPRDDSY LFSLARVRPA IEYALRSVEG NGTGRKLLPP GTRFQVAYED SDCGNRALFS LVDRVAAARG AKPDLILGPV CEYAAAPVAR LASHWDLPML SAGALAAGFQ HKDTEYSHLT RVAPAYAKMG EMMLALFRHH HWSRAALLYS DDKLERNCYF TLEGVHEVFQ EEGLHTSAYN FDETKDLDLD DIVRYIQGSE RVVIMCASGD TIRRIMLAVH RHGMTSGDYA FFNIELFNSS SYGDGSWKRG DKHDFEAKQA YSSLQTVTLL RTAKPEFEKF SMEVKSSVEK QGLNEEDYVN MFVEGFHDAI
Immunohistochemistry: 5-20ug/mL;1:25-100
Immunocytochemistry: 5-20ug/mL;1:25-100
Optimal working dilutions must be determined by end user.
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Western Blot (WB)
(Western Blot: Sample: Recombinant protein.)
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded spinal cord tissue))
Immunohistochemistry (IHC)
(DAB staining on fromalin fixed paraffin- embedded spinal cord tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Spinal cord Tissue))
Immunohistochemistry (IHC)
(DAB staining on IHC-P; Samples: Rat Spinal cord Tissue))
NCBI and Uniprot Product Information
NCBI Description
receptor for natriuretic peptide; may play role in hypertension and neurotransmitter efflux [RGD, Feb 2006]
Uniprot Description
ANP-C: Receptor for the natriuretic peptide hormones, binding with similar affinities atrial natriuretic peptide NPPA/ANP, brain natriuretic peptide NPPB/BNP, and C-type natriuretic peptide NPPC/CNP. May function as a clearance receptor for NPPA, NPPB and NPPC, regulating their local concentrations and effects. May regulate diuresis, blood pressure and skeletal development. Does not have guanylate cyclase activity. Belongs to the ANF receptor family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Membrane protein, integral; Receptor, GPCR
Chromosomal Location of Human Ortholog: 2q16
Cellular Component: integral component of plasma membrane; intracellular; membrane; protein complex
Molecular Function: chloride ion binding; hormone binding; natriuretic peptide receptor activity; peptide binding; peptide hormone binding; peptide receptor activity, G-protein coupled; protein homodimerization activity
Biological Process: G-protein signaling, adenylate cyclase inhibiting pathway; negative regulation of adenylate cyclase activity; negative regulation of smooth muscle cell proliferation; pancreatic juice secretion; phosphoinositide-mediated signaling; phospholipase C-activating G-protein coupled receptor signaling pathway; positive regulation of nitric-oxide synthase activity; regulation of blood pressure; regulation of osteoblast proliferation; skeletal system development
Research Articles on NPR3
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Product Notes
The NPR3 npr3 (Catalog #AAA2028629) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Polyclonal Antibody to Natriuretic Peptide Receptor 3 (NPR3) reacts with Rat and may cross-react with other species as described in the data sheet. AAA Biotech's Natriuretic Peptide Receptor 3 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC), Immunohistochemistry (IHC) Formalin/Paraffin, ELISA (EIA). Western blotting: 0.2-2ug/mL;1:250-2500 Immunohistochemistry: 5-20ug/mL;1:25-100 Immunocytochemistry: 5-20ug/mL;1:25-100 Optimal working dilutions must be determined by end user. . Researchers should empirically determine the suitability of the NPR3 npr3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: Antigen: The target protein is fused with two N-terminal Tags, His-tag and T7-tag and its sequence is listed below. MGSSHHHHHH SSGLVPRGSH MASMTGGQQM GRGS- AQKIEV LVLLPRDDSY LFSLARVRPA IEYALRSVEG NGTGRKLLPP GTRFQVAYED SDCGNRALFS LVDRVAAARG AKPDLILGPV CEYAAAPVAR LASHWDLPML SAGALAAGFQ HKDTEYSHLT RVAPAYAKMG EMMLALFRHH HWSRAALLYS DDKLERNCYF TLEGVHEVFQ EEGLHTSAYN FDETKDLDLD DIVRYIQGSE RVVIMCASGD TIRRIMLAVH RHGMTSGDYA FFNIELFNSS SYGDGSWKRG DKHDFEAKQA YSSLQTVTLL RTAKPEFEKF SMEVKSSVEK QGLNEEDYVN MFVEGFHDAI. It is sometimes possible for the material contained within the vial of "Natriuretic Peptide Receptor 3, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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