Mouse anti-Human NARG2 Polyclonal Antibody | anti-NARG2 antibody

NARG2 (NMDA Receptor-regulated Protein 2, BRCC1, UNQ3101/PRO10100, FLJ11896)

Cat. Num. AAA643077

• Gene Names: NARG2; BRCC1
• Reactivity: Human
• Applications: Western Blot, Immunofluorescence
• Purity: Affinity Purified; Purified by Protein A affinity chromatography.
• Synonyms: NARG2; Polyclonal Antibody; NARG2 (NMDA Receptor-regulated Protein 2; BRCC1; UNQ3101/PRO10100; FLJ11896); Anti -NARG2 (NMDA Receptor-regulated Protein 2; anti-NARG2 antibody

• Host: Mouse
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Specificity: Recognizes human NARG2.
• Purity/Purification: Affinity Purified; Purified by Protein A affinity chromatography.
• Form/Format: Supplied as a liquid in PBS, pH 7.2.
• Sequence: MQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT

• Applicable Applications for anti-NARG2 antibody: Western Blot (WB), Immunofluorescence (IF)
• Application Notes: Suitable for use in Immunofluorescence and Western Blot.; Dilution: Immunofluorescence: 10ug/ml
• Immunogen: Full length human NARG2, aa1-332 (AAH13684.1).
• Preparation and Storage: May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Western Blot (WB)

(Western Blot analysis of NARG2 expression in transfected 293T cell line by NARG2 polyclonal antibody. Lane 1: NARG2 transfected lysate (36.52kD). Lane 2: Non-transfected lysate.)

Immunofluorescence (IF)

(Immunofluorescence of purified antibody to NARG2 on HeLa cell. [antibody concentration 10ug/ml].)

Related Product Information for anti-NARG2 antibody

NARG2 is expressed at relatively high levels in dividing and immature cells, and is down-regulated upon terminal differentiation. NARG2 is a novel (S/T)PXX motif-containing nuclear protein; this motif is present in many transcription factors as well as other regulatory proteins that bind to DNA such as histones and RNA polymerase II. Three different isoforms exist.

Product Categories/Family for anti-NARG2 antibody

Antibodies; Abs to Nuclear Proteins

NCBI and Uniprot Product Information

• NCBI GI #: 66346704
• NCBI GeneID: 79664
• NCBI Accession #: NP_001018099.1
• NCBI GenBank Nucleotide #: NM_001018089.2
• UniProt Accession #: Q659A1; Q05CT1; Q3B7W6; Q63HP4; Q658Q0; Q68CN8; Q6IPW7; Q6UX23; Q71H65; Q96CY5; Q9HAA2; B2RU08
• Molecular Weight: 110,011 Da
• NCBI Official Full Name: NMDA receptor-regulated protein 2 isoform b
• NCBI Official Synonym Full Names: NMDA receptor regulated 2
• NCBI Official Symbol: NARG2
• NCBI Official Synonym Symbols: BRCC1
• NCBI Protein Information: NMDA receptor-regulated protein 2; breast cancer cell 1; NMDA receptor-regulated gene 2
• UniProt Protein Name: NMDA receptor-regulated protein 2
• UniProt Gene Name: NARG2
• UniProt Synonym Gene Names: BRCC1
• UniProt Entry Name: NARG2_HUMAN

Uniprot Description

NARG2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 15q22.2

Cellular Component: Cajal body; transcription elongation factor complex

Molecular Function: protein binding

Biological Process: snRNA transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase III promoter; snRNA transcription from RNA polymerase III promoter